Literature DB >> 1442217

Indication, efficiency and complications of intrathecal pump supported baclofen treatment in spinal spasticity.

L Saltuari1, M Kronenberg, M J Marosi, M Kofler, L Russegger, C Rifici, P Bramanti, F Gerstenbrand.   

Abstract

In 19 patients, who suffered from severe spinal spasticity of different etiologies and did not respond sufficiently to oral antispastic therapy, intrathecal Baclofen test boli were administered. In 11 patients a DAD (Drug Administration Device) [SynchroMedR Model 8611 H, Medtronic Inc. Minneapolis, USA] was implanted. Catheter dislocation or torsion was the most common complication to be observed in these 11 patients. Long term intrathecal Baclofen application was effective in all patients, as reducing spasticity, flexor spasms and spasm induced pain. In some cases the motor performance ameliorated.

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Year:  1992        PMID: 1442217

Source DB:  PubMed          Journal:  Acta Neurol (Napoli)        ISSN: 0001-6276


  5 in total

1.  Cost analysis of the treatment of severe spinal spasticity with a continuous intrathecal baclofen infusion system.

Authors:  T J Postma; D Oenema; S Terpstra; J Bouma; H Kuipers-Upmeijer; M J Staal; B J Middel
Journal:  Pharmacoeconomics       Date:  1999-04       Impact factor: 4.981

2.  Effect of intrathecal baclofen delivered by an implanted programmable pump on health related quality of life in patients with severe spasticity.

Authors:  B Middel; H Kuipers-Upmeijer; J Bouma; M Staal; D Oenema; T Postma; S Terpstra; R Stewart
Journal:  J Neurol Neurosurg Psychiatry       Date:  1997-08       Impact factor: 10.154

3.  Long term effect (more than five years) of intrathecal baclofen on impairment, disability, and quality of life in patients with severe spasticity of spinal origin.

Authors:  A Zahavi; J H B Geertzen; B Middel; M Staal; J S Rietman
Journal:  J Neurol Neurosurg Psychiatry       Date:  2004-11       Impact factor: 10.154

Review 4.  A benefit-risk assessment of baclofen in severe spinal spasticity.

Authors:  Alessandro Dario; Giustino Tomei
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

5.  Pain After Spinal Cord Injury Is Associated With Abnormal Presynaptic Inhibition in the Posterior Nucleus of the Thalamus.

Authors:  Anthony Park; Olivia Uddin; Ying Li; Radi Masri; Asaf Keller
Journal:  J Pain       Date:  2018-03-02       Impact factor: 5.383

  5 in total

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