Literature DB >> 14417081

The effect of enzyme inhibitors on histamine catabolism in man.

S E LINDELL, K NILSSON, B E ROOS, H WESTLING.   

Abstract

The catabolism of histamine was studied in three female psychiatric patients by analysis of the [(14)C]-labelled metabolic products occurring in the urine after a subcutaneous injection of [(14)C]histamine. Each patient was studied before and during treatment with aminoguanidine or iproniazid.Without treatment the patients had a normal histamine catabolism. Aminoguanidine and iproniazid inhibited the oxidation of histamine to imidazoleacetic acid; iproniazid produed a 50% inhibition of the oxidation of methylhistamine to methylimidazoleacetic acid. After iproniazid a large proportion of the injected [C(14)]histamine was excreted as methyl [(14)C]histamine.

Entities:  

Keywords:  HISTAMINASE/antagonists; HISTAMINE/metabolism

Mesh：

Substances：

Year:  1960        PMID： 14417081      PMCID： PMC1481924          DOI： 10.1111/j.1476-5381.1960.tb01255.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  11 in total

1.  The amine oxidases of mammalian plasma.

Authors:  H BLASCHKO; P J FRIEDMAN; R HAWES; K NILSSON
Journal:  J Physiol       Date:  1959-03-03       Impact factor: 5.182

2.  Catabolism of physiological quantities of histamine in vivo.

Authors:  R W SCHAYER
Journal:  Physiol Rev       Date:  1959-01       Impact factor: 37.312

3.  Synthesis and metabolism of a histamine metabolite, 1-methyl-4 (beta-aminoethyl)-imidazole.

Authors:  Z ROTHSCHILD; R W SCHAYER
Journal:  Biochim Biophys Acta       Date:  1958-10

4.  Metabolism of 14C-labelled histamine in pregnant and non-pregnant women.

Authors:  K NILSSON; S E LINDELL; R W SCHAYER; H WESTLING
Journal:  Clin Sci       Date:  1959-05       Impact factor: 6.124

5.  The influence of amine oxidase inhibitors on epinephrine metabolism in man.

Authors:  O RESNICK
Journal:  Ann N Y Acad Sci       Date:  1959-09-17       Impact factor: 5.691

6.  Histamine degradation in tissue extracts from the cat.

Authors:  K M LINDAHL; S E LINDELL; H WESTLING; T WHITE
Journal:  Acta Physiol Scand       Date:  1957-03-07

7.  The metabolism of histidine. III. Urinary metabolites.

Authors:  R C BALDRIDGE; C D TOURTELLOTTE
Journal:  J Biol Chem       Date:  1958-07       Impact factor: 5.157

8.  Metabolism of C14 histamine in man.

Authors:  J A COOPER; R W SCHAYER
Journal:  J Appl Physiol       Date:  1956-11       Impact factor: 3.531

9.  Histamine tolerance in schizophrenia.

Authors:  J D LUCY
Journal:  AMA Arch Neurol Psychiatry       Date:  1954-05

10.  The renal removal of injected [14C] histamine from the blood in dogs.

Authors:  S E LINDELL; R W SCHAYER
Journal:  Br J Pharmacol Chemother       Date:  1958-03
View more
  5 in total

1.  Comparison of the effects of aminoguanidine and L-carnitine treatments on somatosensorial evoked potentials in alloxan-diabetic rats.

Authors:  O Yildiz; M Ozata; A Ozkardeş; G Deniz; M Yildirimkaya; A Corakçi; M Yardim; M A Gündoğan
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1996-10       Impact factor: 3.000

2.  Histamine formation from 14 C-L-histidine in man.

Authors:  B Berg; G Granerus; M B Johansson; H Westling; T White
Journal:  Br J Pharmacol       Date:  1972-10       Impact factor: 8.739

3.  Metabolism of [c]-histamine in heart-lung-liver preparations of cats.

Authors:  B Lilja; S E Lindell
Journal:  Br J Pharmacol Chemother       Date:  1961-04

4.  Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.

Authors:  A H Cross; T P Misko; R F Lin; W F Hickey; J L Trotter; R G Tilton
Journal:  J Clin Invest       Date:  1994-06       Impact factor: 14.808

5.  EFFECTS OF CHLORPROMAZINE AND BROMOLYSERGIC ACID DIETHYLAMIDE ON GASTRIC SECRETION OF ACID INDUCED BY HISTAMINE IN RATS.

Authors:  B O AMURE; M GINSBURG
Journal:  Br J Pharmacol Chemother       Date:  1964-06
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.