Literature DB >> 1441216

The potential of molecular biology for the production of monoclonal antibodies derived from outbred veterinary animals.

M Suter1.   

Abstract

The protein structure of immunoglobulins and the genetics on the regulation of immunoglobulin expression are reviewed. This basic knowledge has led to the development of systems to produce monoclonal antibodies in eukaryotic or prokaryotic cells. The potential and limitations of molecular biology for the understanding of immunoglobulin regulation and for the production of monoclonal antibodies derived from animals of veterinary importance are discussed.

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Year:  1992        PMID: 1441216     DOI: 10.1016/0165-2427(92)90001-7

Source DB:  PubMed          Journal:  Vet Immunol Immunopathol        ISSN: 0165-2427            Impact factor:   2.046


  1 in total

1.  Generation of native bovine mAbs by phage display.

Authors:  P M O'Brien; R Aitken; B W O'Neil; M S Campo
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-19       Impact factor: 11.205

  1 in total

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