Literature DB >> 14409702

Studies on the antigenic properties of complement. I. Demonstration of agglutinating antibodies against guinea pig complement fixed on sensitized sheep erythrocytes.

P G KLEIN, P M BURKHOLDER.   

Abstract

Evidence is presented to show that guinea pig complement fixed on sensitized sheep red cells acts as a specific agglutinogen. Agglutinating antibodies that react with cell-fixed complement can be produced by immunizing rabbits with a complex of stromata-amboceptor-complement or with guinea pig serum globulin. These agglutinins can be removed by precipitation with guinea pig serum. They are, therefore, distinct from immunoconglutinins.

Entities:  

Keywords:  ANTIBODIES; COMPLEMENT

Mesh：

Substances：

Year:  1960        PMID： 14409702      PMCID： PMC2137196          DOI： 10.1084/jem.111.1.93

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  8 in total

1.  [A method for fluorescence-optic demonstration of complement fixation and its use in the histo-immunological demonstration of experimental kidney anaphylaxis].

Authors:  P KLEIN; P BURKHOLDER
Journal:  Dtsch Med Wochenschr       Date:  1959-11-06       Impact factor: 0.628

2.  Preserving fluorescein isocyanate for simplified preparation of fluorescent antibody.

Authors:  M GOLDMAN; R K CARVER
Journal:  Science       Date:  1957-10-25       Impact factor: 47.728

3.  Immunological estimation of a component of complement.

Authors:  H A ELLIS; P G GELL
Journal:  Nature       Date:  1958-06-14       Impact factor: 49.962

4.  Staining of complement and modification of fluorescent antibody procedures.

Authors:  R A GOLDWASSER; C C SHEPARD
Journal:  J Immunol       Date:  1958-02       Impact factor: 5.422

5.  Kinetic studies on immune hemolysis. VII. Decay of EAC'1, 4, 2, fixation of C'3, and other factors influencing the hemolytic action of complement.

Authors:  M M MAYER; L LEVINE; H J RAPP; A A MARUCCI
Journal:  J Immunol       Date:  1954-12       Impact factor: 5.422

6.  The demonstration of an antibody against complement.

Authors:  A P MCKEE; W S JETER
Journal:  J Immunol       Date:  1956-02       Impact factor: 5.422

7.  Studies on the antigenic properties of complement. II. Analysis of specific agglutinins against certain components of guinea pig complement fixed on sensitized sheep erythrocytes.

Authors:  P G KLEIN; P M BURKHOLDER
Journal:  J Exp Med       Date:  1960-01-01       Impact factor: 14.307

8.  Studies on immune hemolysis: preparation of a stable and highly reactive complex of sensitized erythrocytes and the first component of complement (EAC'1): inactivation of cell-fixed C'1 by some complement reagents.

Authors:  P G KLEIN
Journal:  J Exp Med       Date:  1960-01-01       Impact factor: 14.307
  8 in total
  18 in total

1.  THE EFFECTS OF 'ANTI-ANTIBODY' ON IMMUNE HAEMOLYSIS.

Authors:  J A ROMEYN; E ONYSKO
Journal:  Immunology       Date:  1964-05       Impact factor: 7.397

2.  STUDIES ON THE ANTIGENIC PROPERTIES OF COMPLEMENT. III. SPECIFIC INACTIVATION OF CELL-FIXED COMPONENTS OF GUINEA-PIG COMPLEMENT BY ANTI-COMPLEMENT.

Authors:  W OPFERKUCH; P G KLEIN
Journal:  Immunology       Date:  1964-05       Impact factor: 7.397

3.  Complement fixation in diseased tissues. II. Fixation of guinea pig complement in renal lesions of systemic lupus erythematosus.

Authors:  P M BURKHOLDER
Journal:  Am J Pathol       Date:  1963-02       Impact factor: 4.307

4.  [HEMOLYSIS STUDIES WITH S35-LABELLED GUINEA PIG COMPLEMENT: ON THE SUBSTANCE INCREASE FOLLOWING BINDING OF THE 1ST AND 4TH COMPLEMENT COMPONENTS].

Authors:  W OPFERKUCH; H G MUELLER
Journal:  Z Hyg Infektionskr       Date:  1963-10-25

5.  [FLUORESCENCE SEROLOGIC COMPLEMENT FIXATION BY CELL-FAST ANTIBODIES IN TUBERCULOSIS].

Authors:  G GILLISSEN
Journal:  Z Hyg Infektionskr       Date:  1964-12-03

6.  [On the microscopic demonstration of the complement-fixating antigen-antibody complex with fluorescein-labelled anti-complement].

Authors:  H CRAMER; E LANGER
Journal:  Z Zellforch Microsk Anat Histochem       Date:  1961

7.  [On the demonstration of Toxoplasma gondii in the tissue with the aid of labelled fluorescent antibodies (Coons method)].

Authors:  F DALLENBACH; G PIEKARSKI
Journal:  Virchows Arch Pathol Anat Physiol Klin Med       Date:  1960

8.  [Preparation and evaluation of "anticomplement"].

Authors:  P KLEIN; A COLLI
Journal:  Z Hyg Infektionskr       Date:  1961

9.  [Quantitative studies on the direct and indirect fluorescence-serological demonstration of complement fixaction to enterovirus antibody aggregate].

Authors:  F MUELLER
Journal:  Arch Gesamte Virusforsch       Date:  1961

10.  Proliferative glomerulonephritis in children. A correlation of varied clinical and pathologic patterns utilizing light, immunofluorescence, and electron microscopy.

Authors:  P M Burkholder; W D Bradford
Journal:  Am J Pathol       Date:  1969-09       Impact factor: 4.307
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