| Literature DB >> 1440825 |
D D Banker1, P Desai, T A Brawner, R H Decker.
Abstract
From June 1985 to June 1989, sera from 425 cases of acute viral hepatitis were gathered from 2 hospitals in Bombay; 331 sera were positive for hepatitis B surface antigen and immunoglobulin M anti-hepatitis B core antigen, and the donors' disease was diagnosed as hepatitis B. Anti-hepatitis D virus was found in 124 of these sera, and hepatitis D antigen was present in 24 more, conclusively proving the presence of hepatitis delta infection in association with hepatitis B in Bombay. Among the 425 cases of hepatitis, 39 cases of fulminant hepatitis developed, of whom 31 died. Hepatitis B virus (HBV) was the apparent viral infection in 32 of the fulminant cases, and 20 (63%) of them also showed evidence of hepatitis D virus (HDV) infection, suggesting an aggravation of their clinical course due to concurrent HBV and HDV infections.Entities:
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Year: 1992 PMID: 1440825 DOI: 10.1016/0035-9203(92)90251-7
Source DB: PubMed Journal: Trans R Soc Trop Med Hyg ISSN: 0035-9203 Impact factor: 2.184