Literature DB >> 14408116

Antithyroid effects of aminotriazole.

T H JUKES, C B SHAFFER.   

Abstract

Aminotriazole, Like other antithyroid compounds and low-iodine diets, produces adenomatous changes in the thyroid glands of rats when fed continuously for long periods. Such changes are reversible if the antithyroid regime is discontinued. The antithyroid compounds that are naturally present in food are not regarded as causes of cancer.

Entities:  

Keywords:  HERBICIDES/pharmacology; THYROID GLAND/pharmacology

Mesh：

Substances：

Year:  1960        PMID： 14408116     DOI： 10.1126/science.132.3422.296

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

1.  [Metabolism of 3-amino-1,2,4-triazole in rats].

Authors:  W Grunow; H J Altmann; C Böhme
Journal:  Arch Toxicol       Date:  1975-12-18       Impact factor: 5.153

Review 2.  Developmental effects of endocrine-disrupting chemicals in wildlife and humans.

Authors:  T Colborn; F S vom Saal; A M Soto
Journal:  Environ Health Perspect       Date:  1993-10       Impact factor: 9.031

3.  Single neonatal irradiation induces long-term gene expression changes in the thyroid gland, which may be involved in the tumorigenesis.

Authors:  Nariaki Fujimoto; Mutsumi Matsuu-Matsuyama; Masahiro Nakashima
Journal:  Sci Rep       Date:  2021-12-08       Impact factor: 4.379

4.  A carcinogenic potency database of the standardized results of animal bioassays.

Authors:  L S Gold; C B Sawyer; R Magaw; G M Backman; M de Veciana; R Levinson; N K Hooper; W R Havender; L Bernstein; R Peto
Journal:  Environ Health Perspect       Date:  1984-12       Impact factor: 9.031

5.  X-accumulation of labelled aminotriazole in some transplanted tumours in mice.

Authors:  H Tjälve
Journal:  Br J Cancer       Date:  1974-08       Impact factor: 7.640
  5 in total

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