| Literature DB >> 144078 |
R L Ladda, M J Maisels, J H Dossett, Y Dobelle.
Abstract
In individuals with mosaicism for trisomy 21, phenotype-karyotype correlations are unpredictable. Two patients are described--one with typical features of Down's syndrome and the other with severe mental retardation only. Both had normal karyotypes in their peripheral lymphocytes but high percentages of trisomic cells in skin fibroblasts.Entities:
Mesh：
Year: 1977 PMID： 144078 DOI： 10.1111/j.1469-8749.1977.tb08001.x
Source DB: PubMed Journal: Dev Med Child Neurol ISSN： 0012-1622 Impact factor: 5.449