Literature DB >> 1440646

Structure determination and toxicity of a new microcystin from Microcystis aeruginosa strain 205.

J Kiviranta1, M Namikoshi, K Sivonen, W R Evans, W W Carmichael, K L Rinehart.   

Abstract

A new hepatotoxic microcystin was isolated from the cyanobacterium Microcystis aeruginosa strain 205. Its structure was found to be [Dha7]microcystin-RR as determined by amino acid analysis, mass spectrometry and 1H NMR spectroscopy. LD50 value (i.p. mouse) of this toxin was 180 micrograms/kg. The 48 hr lethal concentration (48-hr-LC50) of the toxin for larvae of the yellow fever mosquito, Aedes aegypti, was 14.9 micrograms/ml.

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Year:  1992        PMID: 1440646     DOI: 10.1016/0041-0101(92)90054-9

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  4 in total

1.  Determination of oligopeptide diversity within a natural population of Microcystis spp. (cyanobacteria) by typing single colonies by matrix-assisted laser desorption ionization-time of flight mass spectrometry.

Authors:  J Fastner; M Erhard; H von Döhren
Journal:  Appl Environ Microbiol       Date:  2001-11       Impact factor: 4.792

2.  Algae in mosquito breeding sites and the effectiveness of the mosquito larvicide Bacillus thuringiensis H-14.

Authors:  A Abdel-Hameed; J Kiviranta; K Sivonen; S Niemelä; G Carlberg
Journal:  World J Microbiol Biotechnol       Date:  1993-03       Impact factor: 3.312

3.  Selectivity and potency of microcystin congeners against OATP1B1 and OATP1B3 expressing cancer cells.

Authors:  Timo H J Niedermeyer; Abigail Daily; Monika Swiatecka-Hagenbruch; Jeffrey A Moscow
Journal:  PLoS One       Date:  2014-03-10       Impact factor: 3.240

Review 4.  Structural Diversity, Characterization and Toxicology of Microcystins.

Authors:  Noureddine Bouaïcha; Christopher O Miles; Daniel G Beach; Zineb Labidi; Amina Djabri; Naila Yasmine Benayache; Tri Nguyen-Quang
Journal:  Toxins (Basel)       Date:  2019-12-07       Impact factor: 4.546

  4 in total

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