Literature DB >> 14403718

Enzymatic pathway for the formation of cotinine, a major metabolite of nicotine in rabbit liver.

H B HUCKER, J R GILLETTE, B B BRODIE.   

Abstract

Entities:  

Keywords:  NICOTINE/chemistry

Mesh：

Substances：

Year:  1960        PMID： 14403718

Source DB:  PubMed          Journal:  J Pharmacol Exp Ther        ISSN： 0022-3565            Impact factor:   4.030


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  15 in total

1.  Catalytic mechanism of cytochrome P450 for 5'-hydroxylation of nicotine: fundamental reaction pathways and stereoselectivity.

Authors:  Dongmei Li; Xiaoqin Huang; Keli Han; Chang-Guo Zhan
Journal:  J Am Chem Soc       Date:  2011-04-22       Impact factor: 15.419

Review 2.  Nicotinic receptors containing the alpha7 subunit: a model for rational drug design.

Authors:  G Sharma; S Vijayaraghavan
Journal:  Curr Med Chem       Date:  2008       Impact factor: 4.530

3.  Studies on the time course and the effect of cholinergic and adrenergic receptor blockers on the stimulus effect of nicotine.

Authors:  I D Hirschhorn; J A Rosecrans
Journal:  Psychopharmacologia       Date:  1974

4.  Metabolism of a pharmacologically active pyrrolidine derivative (prolintane) by lactam formation.

Authors:  H B Hucker; S C Stauffer; R E Rhodes
Journal:  Experientia       Date:  1972-04-15

5.  Fundamental reaction pathways for cytochrome P450-catalyzed 5'-hydroxylation and N-demethylation of nicotine.

Authors:  Dongmei Li; Yong Wang; Keli Han; Chang-Guo Zhan
Journal:  J Phys Chem B       Date:  2010-07-15       Impact factor: 2.991

Review 6.  Aspects of the oxidative metabolism of nicotine.

Authors:  G B Neurath
Journal:  Clin Investig       Date:  1994-02

Review 7.  General mechanisms of nicotine-induced fibrogenesis.

Authors:  Kendal Jensen; Damir Nizamutdinov; Micheleine Guerrier; Syeda Afroze; David Dostal; Shannon Glaser
Journal:  FASEB J       Date:  2012-08-20       Impact factor: 5.191

8.  The metabolism of nicotine-delta 1'(5')-iminium ion, in vivo and in vitro.

Authors:  J W Gorrod; A R Hibberd
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1982 Oct-Dec       Impact factor: 2.441

9.  The simultaneous determination of muscle cell pH using a weak acid and weak base.

Authors:  S Adler
Journal:  J Clin Invest       Date:  1972-02       Impact factor: 14.808

10.  The metabolism of [14C] nicotine in the cat.

Authors:  D M Turner
Journal:  Biochem J       Date:  1969-12       Impact factor: 3.857
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