Infection and endoscopy: who infects whom?

Infection is one of the major hazards of endoscopic procedures and is the commonest complication of endoscopic retrograde cholangio-pancreatography (ERCP) causing death. Prevention of endoscopy-associated infections is based on adequate cleaning and disinfection regimens. Scrupulous mechanical cleaning is fundamental; even prolonged chemical disinfection will be ineffective if cleaning has not been adequate. Special measures are required to prevent ERCP-related infections. It is important to recognize various special circumstances that increase a patient's susceptibility to infection and to administer antibiotic prophylaxis when appropriate.