Virus meningo-encephalitis in Slovenia.

A description, based on observations of about 500 cases over seven years, is given of the clinical features of virus meningo-encephalitis as it occurs in Slovenia.The course of the disease is generally diphasic-a prodromal stage being followed, after a quiescent period of a few days, by the meningo-encephalitic stage proper. Blood counts show leucopenia in the prodromal stage and neutrophilic leucocytosis in the meningo-encephalitic stage. Another characteristic feature is the almost regular increase of protein in the cerebrospinal fluid from the onset of the disease.It is pointed out that there is a considerable diversity of clinical phenomena in different patients, which often makes it difficult to diagnose the disease on clinical grounds alone. It is also frequently difficult to differentiate clinically between virus meningo-encephalitis and tuberculous meningitis or poliomyelitis.