| Literature DB >> 143718 |
M M Beyer, A D Steinberg, A D Nicastri, E A Friedman.
Abstract
Male F1 New Zealand Black X New Zealand White mice, which spontaneously develop immune complex renal disease, underwent unilateral nephrectomy at 3 months of age and were compared with sham-operated controls. At 12 months of age only 24% of mice with a single kidney were alive, while 85% of sham-operated controls survived to the same age. Unilaterally nephrectomized mice had more severe renal histologic changes, as shown by light and immunofluorescence microscopy.Entities:
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Year: 1977 PMID： 143718 DOI： 10.1126/science.143718
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728