| Literature DB >> 14367685 |
S P MARTIN, C D COOPER, S N CHAUDHURI, R GREEN.
Abstract
The alterations in succinic dehydrogenase activity during the course of infection with Mycobacterium tuberculosis strains H37Rv and BCG, as well as with dead bacilli, has been described. A tissue factor has been described which is prepared from normal bovine kidney and will restore enzyme activity in vitro. This factor is prepared by chromatographic analysis and contains a nucleotide with an ultraviolet absorption maxima at 250 mmicro (pH 3) and a free sulfhydryl group. The role of this factor in the response to tuberculosis is discussed.Entities:
Keywords: DEHYDROGENASES; KIDNEYS/metabolism; TUBERCULOSIS, RENAL/experimental
Mesh:
Substances:
Year: 1955 PMID: 14367685 PMCID: PMC2136487 DOI: 10.1084/jem.101.6.639
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307