| Literature DB >> 1436058 |
S Swaminathan1, W Furey, J Pletcher, M Sax.
Abstract
The three-dimensional structure of staphylococcal enterotoxin B, which is both a toxin and a super-antigen, has been determined to a resolution of 2.5 A. The unusual main-chain fold containing two domains may represent a general motif adopted by all staphylococcal enterotoxins. The T-cell receptor binding site encompasses a shallow cavity formed by both domains. The MHCII molecule binds to an adjacent site. Another cavity with possible biological activity was also identified.Mesh：
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Year: 1992 PMID： 1436058 DOI： 10.1038/359801a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962