FURTHER INVESTIGATIONS OF THE INCORPORATION OF (1-14C)ACETATE INTO THE LIPIDS OF THE SILKWORM BOMBYX MORI L.

1. After the injection of sodium [1-(14)C]acetate, the highest incorporation of (14)C into the lipids of the silkworm was observed after 24hr. 2. The specific radioactivity of the palmitic acid fraction was greater and increased more rapidly than that of the stearic acid fraction, which was consistent with the precursor-product relationship to be expected on the basis of current concepts of fatty acid synthesis in vivo. 3. The results indicate the probability of synthesis of lipid components in tissues other than the fat body. 4. Fractionation studies indicate considerable differences in the rate of incorporation of [1-(14)C]acetate into neutral lipids and phospholipids between larvae and pupae as well as among tissues of larvae. 5. The rate of incorporation of [1-(14)C]acetate remains constant throughout pupal development.