Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 POLYOMA-LIKE VIRIONS IN HUMAN DEMYELINATING BRAIN DISEASE.

Literature DB >> 14339302

POLYOMA-LIKE VIRIONS IN HUMAN DEMYELINATING BRAIN DISEASE.

Abstract

Specimens of brain tissue obtained at autopsy from three patients suffering from progressive multifocal leukoencephalopathy (PML) were examined by electron microscopy. In specimens from all three cases particles similar to those of the papova virus group were present, confirming previous observations. By the negative staining method it was possible to define the morphological characteristics of the particles more precisely and it was shown that they are structurally similar to virions of the polyoma-SV40-K type. The need is emphasized for obtaining fresh unfixed diseased tissue from persons suffering from PML in order that the biological properties of the particles can be investigated.

Entities: Disease Species

Keywords: CEREBRAL SCLEROSIS, DIFFUSE; DEMYELINATION; MICROBIOLOGY; MICROSCOPY, ELECTRON; PATHOLOGY; POLYOMA VIRUS; STAINS AND STAINING

Mesh：

Substances：
Coloring Agents

Year: 1965 PMID： 14339302 PMCID： PMC1928746

Source DB: PubMed Journal: Can Med Assoc J ISSN： 0008-4409 Impact factor: 8.262

11 in total

1. Proposals.

Authors: D L CASPAR; R DULBECCO; A KLUG; A LWOFF; M G STOKER; P TOURNIER; P WILDY
Journal: Cold Spring Harb Symp Quant Biol Date: 1962

2. PROGRESSIVE MULTIFOCAL LEUCOENCEPHALOPATHY AND PRIMARY HYPERSPLENISM. WITH A NOTE ON THE ASSOCIATION BETWEEN DISEASE OF THE RETICULOENDOTHELIAL SYSTEM AND PROGRESSIVE MULTIFOCAL LEUCOENCEPHALOPATHY.

Authors: V F WEINSTEIN; A L WOOLF; M J MEYNELL
Journal: J Clin Pathol Date: 1963-09 Impact factor: 3.411

10. Infectious leukoencephalitis. A critical comparison of certain experimental and naturally-occurring viral leukoencephalitides with experimental allergic encephalomyelitis.

Authors: B H WAKSMAN; R D ADAMS
Journal: J Neuropathol Exp Neurol Date: 1962-10 Impact factor: 3.685

25 in total

POLYOMA-LIKE VIRIONS IN HUMAN DEMYELINATING BRAIN DISEASE.

1. Proposals.

2. PROGRESSIVE MULTIFOCAL LEUCOENCEPHALOPATHY AND PRIMARY HYPERSPLENISM. WITH A NOTE ON THE ASSOCIATION BETWEEN DISEASE OF THE RETICULOENDOTHELIAL SYSTEM AND PROGRESSIVE MULTIFOCAL LEUCOENCEPHALOPATHY.

3. A COMPARATIVE STUDY OF POLYOMA AND PAPILLOMA VIRUSES.

4. [PROGRESSIVE MULTIFOCAL LEUKO-ENCEPHALOPATHY].

5. Progressive multifocal leukoencephalopathy.

6. Leukoencephalopathy associated with Hodgkin's disease.

7. Cerebral demyelination associated with disorders of the reticuloendothelial system.

8. A negative staining method for high resolution electron microscopy of viruses.

9. Papova virus group.

10. Infectious leukoencephalitis. A critical comparison of certain experimental and naturally-occurring viral leukoencephalitides with experimental allergic encephalomyelitis.

1. The remote effects of cancer on the nervous system.

2. Another virus in C.N.s.?

3. Papovaviruses and human disease.

4. Demonstration of virus particles in human genital warts.

5. Viral infections of the nervous system.

6. Factors in the host-virus relationship which may affect the course of an infection.

7. Acute viral infections of the nervous system.

8. Polyoma-like virions in a human demyelinating disease.

9. Sulphamethoxazole combined with 2-4-diamino-pyrimidines in the treatment of gonorrhoea.

10. Viruses and the neuroglia with special reference to scrapie, kuru and disseminated sclerosis.