Literature DB >> 1433532

Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.

H Y Naim1, B Amarneh, N T Ktistakis, M G Roth.   

Abstract

Mutagenesis studies indicated that the three cytoplasmic cysteines of the influenza virus A/Japan/305/57 hemagglutinin (HA) are all palmitylated, but to an unequal extent. Replacement of all three cysteines abolished palmitylation, but affected neither HA biosynthesis nor function. Palmitate was not required for HA to be incorporated into virions.

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Year:  1992        PMID： 1433532      PMCID： PMC240475     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  19 in total

1.  Deacylation of the hemagglutinin of influenza A/Aichi/2/68 has no effect on membrane fusion properties.

Authors:  D A Steinhauer; S A Wharton; D C Wiley; J J Skehel
Journal:  Virology       Date:  1991-09       Impact factor: 3.616

2.  Alterations to influenza virus hemagglutinin cytoplasmic tail modulate virus infectivity.

Authors:  D A Simpson; R A Lamb
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

3.  Evidence from lateral mobility studies for dynamic interactions of a mutant influenza hemagglutinin with coated pits.

Authors:  E Fire; D E Zwart; M G Roth; Y I Henis
Journal:  J Cell Biol       Date:  1991-12       Impact factor: 10.539

4.  Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors:  T A Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

5.  Physiological characterization of influenza virus temperature-sensitive mutants defective in the haemagglutinin gene.

Authors:  M Ueda; A Sugiura
Journal:  J Gen Virol       Date:  1984-11       Impact factor: 3.891

6.  Influenza virus ts61S hemagglutinin is significantly defective in polypeptide folding and intracellular transport at the permissive temperature.

Authors:  D A Simpson; R A Lamb
Journal:  Virology       Date:  1991-11       Impact factor: 3.616

7.  Site-specific mutagenesis identifies three cysteine residues in the cytoplasmic tail as acylation sites of influenza virus hemagglutinin.

Authors:  M Veit; E Kretzschmar; K Kuroda; W Garten; M F Schmidt; H D Klenk; R Rott
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

8.  The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors.

Authors:  C G Davis; M A Lehrman; D W Russell; R G Anderson; M S Brown; J L Goldstein
Journal:  Cell       Date:  1986-04-11       Impact factor: 41.582

9.  Dynamics and longevity of the glycolipid-anchored membrane protein, Thy-1.

Authors:  P Lemansky; S H Fatemi; B Gorican; S Meyale; R Rossero; A M Tartakoff
Journal:  J Cell Biol       Date:  1990-05       Impact factor: 10.539

10.  Folding of influenza hemagglutinin in the endoplasmic reticulum.

Authors:  I Braakman; H Hoover-Litty; K R Wagner; A Helenius
Journal:  J Cell Biol       Date:  1991-08       Impact factor: 10.539
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  30 in total

1.  VIP17/MAL, a lipid raft-associated protein, is involved in apical transport in MDCK cells.

Authors:  K H Cheong; D Zacchetti; E E Schneeberger; K Simons
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-25       Impact factor: 11.205

2.  The carboxy-terminal domain of glycoprotein N of human cytomegalovirus is required for virion morphogenesis.

Authors:  Michael Mach; Karolina Osinski; Barbara Kropff; Ursula Schloetzer-Schrehardt; Magdalena Krzyzaniak; William Britt
Journal:  J Virol       Date:  2007-01-17       Impact factor: 5.103

3.  Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain.

Authors:  P Scheiffele; M G Roth; K Simons
Journal:  EMBO J       Date:  1997-09-15       Impact factor: 11.598

4.  Palmitoylation, membrane-proximal basic residues, and transmembrane glycine residues in the reovirus p10 protein are essential for syncytium formation.

Authors:  Maya Shmulevitz; Jayme Salsman; Roy Duncan
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

5.  Elongation of the cytoplasmic tail interferes with the fusion activity of influenza virus hemagglutinin.

Authors:  M Ohuchi; C Fischer; R Ohuchi; A Herwig; H D Klenk
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

6.  Palmitylation of the influenza virus hemagglutinin (H3) is not essential for virus assembly or infectivity.

Authors:  H Jin; K Subbarao; S Bagai; G P Leser; B R Murphy; R A Lamb
Journal:  J Virol       Date:  1996-03       Impact factor: 5.103

7.  Apical budding of a recombinant influenza A virus expressing a hemagglutinin protein with a basolateral localization signal.

Authors:  Rosalia Mora; Enrique Rodriguez-Boulan; Peter Palese; Adolfo García-Sastre
Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

8.  Palmitoylation of the Rous sarcoma virus transmembrane glycoprotein is required for protein stability and virus infectivity.

Authors:  C Ochsenbauer-Jambor; D C Miller; C R Roberts; S S Rhee; E Hunter
Journal:  J Virol       Date:  2001-12       Impact factor: 5.103

9.  Basis for selective incorporation of glycoproteins into the influenza virus envelope.

Authors:  H Y Naim; M G Roth
Journal:  J Virol       Date:  1993-08       Impact factor: 5.103

10.  Syntaxin is efficiently excluded from sphingomyelin-enriched domains in supported lipid bilayers containing cholesterol.

Authors:  D E Saslowsky; J C Lawrence; R M Henderson; J M Edwardson
Journal:  J Membr Biol       Date:  2003-08-01       Impact factor: 1.843
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