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Literature DB >> 14333570

BIOCHEMICAL STUDIES OF TOXIC AGENTS. THE METABOLISM OF IODOMETHANE.

Abstract

1. The metabolism of iodomethane has been studied after the administration of the compound to rats by subcutaneous injection. 2. The urinary excretion of S-methylcysteine, methylmercapturic acid, methylthioacetic acid and N-(methylthioacetyl)glycine has been demonstrated by paper chromatography. 3. Methylmercapturic acid and N-(methylthioacetyl)glycine have been isolated from the urine of the dosed animals. 4. The methylthio compounds detected represented about 2% of the iodomethane administered.

Entities: Chemical Species

Keywords: CHROMATOGRAPHY; EXCRETION; EXPERIMENTAL LAB STUDY; IODIDES; METABOLISM; RATS; SULFHYDRYL COMPOUNDS; URINE

Mesh：

Substances：

Year: 1965 PMID： 14333570 PMCID： PMC1215179 DOI： 10.1042/bj0950077

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

13 in total

1. THE METABOLISM OF S-METHYL-L-CYSTEINE IN THE RAT.

Authors: E A BARNSLEY
Journal: Biochim Biophys Acta Date: 1964-07-15

2. Biochemical studies of toxic agents. 14. The biosynthesis of ethylmercapturic acid.

Authors: A E THOMSON; E A BARNSLEY; L YOUNG
Journal: Biochem J Date: 1963-01 Impact factor: 3.857

3. The formation of mercapturic acids. 3. N-Acetylation of S-substituted cysteines in the rabbit, rat and guinea pig.

Authors: H G BRAY; T J FRANKLIN; S P JAMES
Journal: Biochem J Date: 1959-11 Impact factor: 3.857

4. The analysis of urinary 17-oxo steroids by gradient elution.

Authors: A E KELLIE; A P WADE
Journal: Biochem J Date: 1957-06 Impact factor: 3.857

5. Effects of methyl bromide on phosphorus metabolism in the adult housefly, Musca domestica L.

Authors: F P WINTERINGHAM; G C HELLYER; M A McKAY
Journal: Biochem J Date: 1958-08 Impact factor: 3.857

6. (+)-(S-methyl-L-cysteine S-oxide) in cabbage.

Authors: R L SYNGE; J C WOOD
Journal: Biochem J Date: 1956-10 Impact factor: 3.857

7. Toxic liver injury and carcinogenesis. Methylation of proteins of rat-liver slices by dimethylnitrosamine in vitro.

Authors: P N MAGEE; T HULTIN
Journal: Biochem J Date: 1962-04 Impact factor: 3.857

8. Formation of mercapturic acids. 5. Metabolism of some halogenoparaffins and nitroparaffins.

Authors: H G Bray; J C Caygill; S P James; P B Wood
Journal: Biochem J Date: 1964-01 Impact factor: 3.857

9. Biochemical studies of toxic agents. 15. The biosynthesis of ethylmercapturic acid sulphoxide.

Authors: E A Barnsley; A E Thomson; L Young
Journal: Biochem J Date: 1964-03 Impact factor: 3.857

10. A micro-artificial rumen for isotopic experiments.

Authors: R M Dawson; P F Ward; T W Scott
Journal: Biochem J Date: 1964-01 Impact factor: 3.857

5 in total

1. [Cancerogenic alkylating substances. 3. Alkyl-halogenides, -sulfates, -sulfonates and strained heterocyclic compounds].

Authors: H Druckrey; H Kruse; R Preussmann; S Ivankovic; C Landschütz
Journal: Z Krebsforsch Date: 1970

2. Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning.

Authors: R Garnier; M O Rambourg-Schepens; A Müller; E Hallier
Journal: Occup Environ Med Date: 1996-03 Impact factor: 4.402