| Literature DB >> 1433268 |
C J Miller1, N J Alexander, P Vogel, J Anderson, P A Marx.
Abstract
To understand the biologic processes involved in transmission of HIV, we examined the genital tracts of chronically infected female macaques and localized SIV-infected cells. SIV was found in the genital tract of 12 of 16 animals and SIV-infected cells were located in the cervix and vagina. Inoculation of cell-free SIV into the blind vaginal pouch of hysterectomized macaques resulted in systemic infection. We propose a hypothesis to explain the early events in the genital transmission of SIV.Entities:
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Year: 1992 PMID： 1433268
Source DB: PubMed Journal: J Med Primatol ISSN： 0047-2565 Impact factor: 0.667