Literature DB >> 1433227

Screening and genetic counselling for relatives of patients with breast cancer in a family cancer clinic.

R S Houlston1, L Lemoine, E McCarter, S Harrington, K MacDermot, J Hinton, L Berger, J Slack.   

Abstract

Family history is the major risk factor in the aetiology of breast cancer. Breast screening is currently available to women from the age of 50 to 64 through the National Breast Screening Programme. There is, however, an equivalent risk of developing breast cancer below 50 for first degree relatives of women diagnosed with breast cancer premenopausally. We have estimated the risk of breast cancer for relatives of women affected at different ages and used these to establish a family cancer clinic offering breast screening based on individual risk. In three years we have seen 851 patients. Compliance for annual radiology was in excess of 83% over this period and of five cancers detected one had a lump at presentation, two developed interval breast lumps, and two were asymptomatic.

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Year:  1992        PMID: 1433227      PMCID: PMC1016124          DOI: 10.1136/jmg.29.10.691

Source DB:  PubMed          Journal:  J Med Genet        ISSN: 0022-2593            Impact factor:   6.318


  19 in total

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Authors:  R S Houlston; E McCarter; S Parbhoo; J H Scurr; J Slack
Journal:  J Med Genet       Date:  1992-03       Impact factor: 6.318

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Authors:  L J Fallowfield; A Rodway; M Baum
Journal:  J R Soc Med       Date:  1990-09       Impact factor: 18.000

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  4 in total

1.  Management of women at increased risk for breast cancer: preliminary results from a new program.

Authors:  P L Chart; E Franssen
Journal:  CMAJ       Date:  1997-11-01       Impact factor: 8.262

2.  Familial breast cancer: a controlled study of risk perception, psychological morbidity and health beliefs in women attending for genetic counselling.

Authors:  S Lloyd; M Watson; B Waites; L Meyer; R Eeles; S Ebbs; A Tylee
Journal:  Br J Cancer       Date:  1996-08       Impact factor: 7.640

3.  Saliva samples as a source of DNA for high throughput genotyping: an acceptable and sufficient means in improvement of risk estimation throughout mammographic diagnostics.

Authors:  U G Poehls; C C Hack; A B Ekici; M W Beckmann; P A Fasching; M Ruebner; H Huebner
Journal:  Eur J Med Res       Date:  2018-04-27       Impact factor: 2.175

4.  Breast cancer risk estimation in families with history of breast cancer.

Authors:  T Muhonen; H Eerola; P Vehmanen; H Nevanlinna; K Aktan; C Blomqvist; H Kääriäinen; S Pyrhönen
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

  4 in total

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