| Literature DB >> 1433196 |
T A Blizzard1, G M Margiatto, H Mrozik, W L Shoop, R A Frankshun, M H Fisher.
Abstract
Chemical conversion of the potent anthelmintic natural products avermectin B1 (1) and avermectin B2 (3) to the corresponding 13-epi analogs (15 and 9) is described. The novel analogs retain the full potency of the natural products but are substantially safer.Entities:
Mesh：
Substances：
Year: 1992 PMID： 1433196 DOI： 10.1021/jm00099a014
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446