Literature DB >> 1433059

Laxative induced diarrhoea--a neglected diagnosis.

A Duncan1, A J Morris, A Cameron, M J Stewart, W G Brydon, R I Russell.   

Abstract

A laxative screening service was established and offered to gastroenterologists in hospitals covering the West and Central belt of Scotland. The prevalence of laxative induced diarrhoea was assessed in two populations and was found to be 4% in new patients presenting to a gastroenterology clinic with diarrhoea and 20% in patients already under investigation of chronic idiopathic diarrhoea. A high rate of missed diagnosis of laxative induced diarrhoea (71%) and a low request rate (eight per annum) confirm the low clinical awareness of this diagnosis. We found potential savings of 80% of the cost of investigations subsequently ordered which could have been avoided by performing laxative screens on all patients presenting with diarrhoea. The introduction of such a screening policy is recommended as a cost-effective measure.

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Year:  1992        PMID: 1433059      PMCID: PMC1294723          DOI: 10.1177/014107689208500408

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   18.000


  13 in total

1.  Diagnosis of the abuse of magnesium and stimulant laxatives.

Authors:  A Duncan; A Cameron; M J Stewart; R I Russell
Journal:  Ann Clin Biochem       Date:  1991-11       Impact factor: 2.057

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Journal:  Gut       Date:  1974-09       Impact factor: 23.059

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Journal:  Ann Clin Biochem       Date:  1987-01       Impact factor: 2.057

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Authors:  K J Moriarty; D B Silk
Journal:  Dig Dis       Date:  1988       Impact factor: 2.404

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Journal:  Cleve Clin Q       Date:  1984

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Journal:  Clin Gastroenterol       Date:  1986-07

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Authors:  K Ladefoged; O B Schaffalitzky de Muckadell; S Jarnum
Journal:  Scand J Gastroenterol       Date:  1987-09       Impact factor: 2.423

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Authors:  J H Cummings; G E Sladen; O F James; M Sarner; J J Misiewicz
Journal:  Br Med J       Date:  1974-03-23

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Journal:  Gastroenterology       Date:  1980-02       Impact factor: 22.682

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Authors:  G J Krejs; J H Walsh; S G Morawski; J S Fordtran
Journal:  Am J Dig Dis       Date:  1977-04
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  5 in total

1.  Guidelines for the investigation of chronic diarrhoea, 2nd edition.

Authors:  P D Thomas; A Forbes; J Green; P Howdle; R Long; R Playford; M Sheridan; R Stevens; R Valori; J Walters; G M Addison; P Hill; G Brydon
Journal:  Gut       Date:  2003-07       Impact factor: 23.059

Review 2.  Gastroenterology services in the UK. The burden of disease, and the organisation and delivery of services for gastrointestinal and liver disorders: a review of the evidence.

Authors:  J G Williams; S E Roberts; M F Ali; W Y Cheung; D R Cohen; G Demery; A Edwards; M Greer; M D Hellier; H A Hutchings; B Ip; M F Longo; I T Russell; H A Snooks; J C Williams
Journal:  Gut       Date:  2007-02       Impact factor: 23.059

Review 3.  Laxative abuse: epidemiology, diagnosis and management.

Authors:  James L Roerig; Kristine J Steffen; James E Mitchell; Christie Zunker
Journal:  Drugs       Date:  2010-08-20       Impact factor: 9.546

Review 4.  The health-related quality of life and economic burden of constipation.

Authors:  Cheryl Dennison; Manishi Prasad; Andrew Lloyd; Samir K Bhattacharyya; Ravinder Dhawan; Karin Coyne
Journal:  Pharmacoeconomics       Date:  2005       Impact factor: 4.981

5.  Cost-effectiveness of prucalopride in the treatment of chronic constipation in the Netherlands.

Authors:  Mark J C Nuijten; Dominique J Dubois; Alain Joseph; Lieven Annemans
Journal:  Front Pharmacol       Date:  2015-04-14       Impact factor: 5.810

  5 in total

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