| Literature DB >> 14330531 |
J H OPPEHNEIMER, M I SURKS, G BERNSTEIN, J C SMITY.
Abstract
The metabolism of (131)I-labeled thyroxine-binding prealbumin was studied in four normal subjects and in five hospitalized patients with nonthyroidal disease. The average half-time of total-body thyroxine-binding prealbumin, calculated on the basis of a two-compartmental model, was 1.90 daysin normal subjects. Increased fractional degradation or diminished synthesis, or both, contributed to the depression of thyroxine-binding prealbumin in the serum of patients with nonthyroidal disorders.Entities:
Keywords: PROTEIN BINDING; PROTEIN METABOLISM; SERUM ALBUMIN, RADIO-IODINATED; THYROXINE
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Year: 1965 PMID: 14330531 DOI: 10.1126/science.149.3685.748
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728