Literature DB >> 14326086

NEOCARZINOSTATIN, AN ANTITUMOR ANTIBIOTIC OF HIGH MOLECULAR WEIGHT. ISOLATION, PHYSIOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES.

N ISHIDA, K MIYAZAKI, K KUMAGAI, M RIKIMARU.   

Abstract

Entities:  

Keywords:  ANTIBIOTICS; ANTINEOPLASTIC AGENTS; ASCITES; EXPERIMENTAL LAB STUDY; LEUKEMIA, EXPERIMENTAL; MICE; PHARMACOLOGY; SARCINA; SARCOMA 180, CROCKER; STAPHYLOCOCCUS; STREPTOMYCES; TISSUE CULTURE

Mesh:

Substances:

Year:  1965        PMID: 14326086

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


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  32 in total

1.  Cloning, sequencing, and functional analysis of an iterative type I polyketide synthase gene cluster for biosynthesis of the antitumor chlorinated polyenone neocarzilin in "Streptomyces carzinostaticus".

Authors:  Miyuki Otsuka; Koji Ichinose; Isao Fujii; Yutaka Ebizuka
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

2.  Nucleotide specificity in DNA scission by neocarzinostatin.

Authors:  T Hatayama; I H Goldberg; M Takeshita; A P Grollman
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

Review 3.  New drugs under clinical evaluation in the United States.

Authors:  S K Carter
Journal:  Cancer Chemother Pharmacol       Date:  1978       Impact factor: 3.333

4.  Cold instability of aponeocarzinostatin and its stabilization by labile chromophore.

Authors:  Kandaswamy Jayachithra; Thallampuranam Krishnaswamy Suresh Kumar; Ta-Jung Lu; Chin Yu; Der-Hang Chin
Journal:  Biophys J       Date:  2005-04-08       Impact factor: 4.033

5.  "Concerted" transition state, stepwise mechanism. Dynamics effects in C2-C6 enyne allene cyclizations.

Authors:  Tefsit Bekele; Chad F Christian; Mark A Lipton; Daniel A Singleton
Journal:  J Am Chem Soc       Date:  2005-06-29       Impact factor: 15.419

6.  Base substitution mutations induced in the cI gene of lambda phage by neocarzinostatin chromophore: correlation with depyrimidination hotspots at the sequence AGC.

Authors:  L F Povirk; I H Goldberg
Journal:  Nucleic Acids Res       Date:  1986-02-11       Impact factor: 16.971

7.  Electron microscopic observations of neocarzinostatin treated Burkitt lymphoma cells.

Authors:  M Shamoto; Y Kawai; A Kato
Journal:  Experientia       Date:  1973-02-15

8.  Partial sequence of the tyrosine region of neocarzinostatin.

Authors:  C B Glaser; H Maeda; J Meienhofer; H D Niall
Journal:  Experientia       Date:  1972-07-15

9.  Biogenesis of an antitumor antibiotic protein, neocarzinostatin.

Authors:  K Kudo; M Kikuchi; N Ishida
Journal:  Antimicrob Agents Chemother       Date:  1972-04       Impact factor: 5.191

10.  Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.

Authors:  Yinggang Luo; Shuangjun Lin; Jian Zhang; Heather A Cooke; Steven D Bruner; Ben Shen
Journal:  J Biol Chem       Date:  2008-04-03       Impact factor: 5.157

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