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Literature DB >> 14325877

EFFECTS OF MINERALS ON NEOMYCIN PRODUCTION BY STREPTOMYCES FRADIAE.

Abstract

A study was made on the mineral requirements of Streptomyces fradiae strain 3535 for neomycin production. It was observed that optimal levels of the elements Ca, Fe, and Zn per milliliter of a synthetic medium for neomycin production were 10.8, 1.0, and 0.115 mug, respectively. K(2)HPO(4) was required at a concentration of 0.1% for maximal yield of neomycin, whereas NaCl and the metals Mn and Cu were without any effect. High doses of Zn (0.23 mug/ml or above) caused destruction of neomycin after the fifth day of fermentation.

Entities: Chemical Species

Keywords: CALCIUM; CALCIUM CHLORIDE; COPPER; CULTURE MEDIA; EXPERIMENTAL LAB STUDY; FERMENTATION; HYDROGEN-ION CONCENTRATION; IRON; MANGANESE; METABOLISM; NEOMYCIN; PHARMACOLOGY; PHOSPHATES; POTASSIUM; SODIUM CHLORIDE; STREPTOMYCES; ZINC

Mesh：

Substances：

Year: 1965 PMID： 14325877 PMCID： PMC1058219 DOI： 10.1128/am.13.2.190-193.1965

Source DB: PubMed Journal: Appl Microbiol ISSN： 0003-6919

13 in total

8. Antibacterial, Antifungal and Antibiofilm Activities of Silver Nanoparticles Supported by Crude Bioactive Metabolites of Bionanofactories Isolated from Lake Mariout.

Authors: Marwa Eltarahony; Amany Ibrahim; Hadeel El-Shall; Eman Ibrahim; Fayez Althobaiti; Eman Fayad
Journal: Molecules Date: 2021-05-19 Impact factor: 4.411

9. Optimization of Medium Composition for the Production of Neomycin by Streptomyces fradiae NCIM 2418 in Solid State Fermentation.

Authors: B M Vastrad; S E Neelagund
Journal: Biotechnol Res Int Date: 2014-06-09

9 in total

EFFECTS OF MINERALS ON NEOMYCIN PRODUCTION BY STREPTOMYCES FRADIAE.

1. The effect of deficiency of iron, zinc and manganese on the growth and morphology of Nocardia opaca.

2. Trace element requirements of Bacillus subtilis for mycobacillin formation.

3. A b-type cytochrome form Streptomyces fradiae.

4. The role of nutrition in the synthesis of actinomycin.

5. Trace elements and streptomycin production.

6. Grisein, an Antibiotic Produced by Certain Strains of Streptomyces griseus.

7. Studies on the Physiology of a Streptomycin-producing Strain of Streptomyces griseus on Proline Medium.

8. NEOMYCIN-PRODUCTION AND ANTIBIOTIC PROPERTIES.

9. The accumulation of salicylic acid by mycobacteria during growth on an iron-deficient medium.

10. Neomycin, a New Antibiotic Active against Streptomycin-Resistant Bacteria, including Tuberculosis Organisms.

1. Utilization of carbon and nitrogen-containing compounds for neomycin production by Streptomyces fradiae.

2. Utilization of carbon and nitrogen sources by Streptomyces kanamyceticus for kanamycin production.

3. Mineral nutrition of Streptomyces kanamyceticus for kanamycin formation.

4. Effect of some inhibitors on kanamycin formation by Streptomyces kanamyceticus.

5. Regulation of scytophycin accumulation in cultures of Scytonema ocellatum. II. Nutrient requirements.

6. Development of a chemically defined medium for the synthesis of actinomycin D by Streptomyces parvulus.

7. Optimization of Culturing Conditions for Improved Production of Bioactive Metabolites by Pseudonocardia sp. VUK-10.

8. Antibacterial, Antifungal and Antibiofilm Activities of Silver Nanoparticles Supported by Crude Bioactive Metabolites of Bionanofactories Isolated from Lake Mariout.

9. Optimization of Medium Composition for the Production of Neomycin by Streptomyces fradiae NCIM 2418 in Solid State Fermentation.