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Literature DB >> 14319406

THE ORIGIN OF THE CELLS IN THE EFFERENT LYMPH FROM A SINGLE LYMPH NODE.

Abstract

The popliteal nodes of sheep were perfused continuously for over 100 hours with a solution containing (3)H-thymidine. The labelling pattern of the lymphocytes in the efferent lymph from the perfused nodes showed that under normal conditions not more than 4 per cent of these lymphocytes were actually produced in the node. The transitional cells, large lymphocytes and cells of the plasma cell series which appeared in the lymph following antigenic stimulation of the node were all produced in the node.

Entities: Chemical Disease Species

Keywords: DNA; EXPERIMENTAL LAB STUDY; LYMPH; LYMPH NODES; LYMPHOCYTES; PERFUSION; PHOTOMICROGRAPHY; PLASMA CELLS; RADIOAUTOGRAPHY; SHEEP; THYMIDINE; TRITIUM

Mesh：

Substances：

Year: 1965 PMID： 14319406 PMCID： PMC2138009 DOI： 10.1084/jem.121.6.901

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

8 in total

1. EFFECT OF X-IRRADIATION OF THE POPLITEAL LYMPH-NODE ON ITS OUTPUT OF LYMPHOCYTES AND IMMUNOLOGICAL RESPONSIVENESS.

Authors: J G HALL; B MORRIS
Journal: Lancet Date: 1964-05-16 Impact factor: 79.321

2. THE ROUTE OF RE-CIRCULATION OF LYMPHOCYTES IN THE RAT.

Authors: J L GOWANS; E J KNIGHT
Journal: Proc R Soc Lond B Biol Sci Date: 1964-01-14

3. THE MIGRATION OF LYMPHOCYTES THROUGH THE ENDOTHELIUM OF VENULES IN LYMPH NODES: AN ELECTRON MICROSCOPE STUDY.

Authors: V T MARCHESI; J L GOWANS
Journal: Proc R Soc Lond B Biol Sci Date: 1964-01-14

4. Initiation of immune responses by small lymphocytes.

Authors: J L GOWANS; D D McGREGOR; D M COWEN
Journal: Nature Date: 1962-11-17 Impact factor: 49.962

5. The lymph-borne cells of the immune response.

Authors: J G HALL; B MORRIS
Journal: Q J Exp Physiol Cogn Med Sci Date: 1963-07

6. The output of cells in lymph from the popliteal node of sheep.

Authors: J G HALL; B MORRIS
Journal: Q J Exp Physiol Cogn Med Sci Date: 1962-10

7. The effect of the continuous re-infusion of lymph and lymphocytes on the output of lymphocytes from the thoracic duct of unanaesthetized rats.

Authors: J L GOWANS
Journal: Br J Exp Pathol Date: 1957-02

8. The stripping-film technique of autoradiography.

Authors: S R PELC
Journal: Int J Appl Radiat Isot Date: 1956-11

8 in total

64 in total

Review 1. Local immune responses in afferent and efferent lymph.

Authors: D M Haig; J Hopkins; H R Miller
Journal: Immunology Date: 1999-02 Impact factor: 7.397

2. Evidence of CXC, CC and C chemokine production by lymphatic endothelial cells.

Authors: Sabrina Mancardi; Elena Vecile; Nelson Dusetti; Ezequiel Calvo; Giorgio Stanta; Oscar R Burrone; Aldo Dobrina
Journal: Immunology Date: 2003-04 Impact factor: 7.397

Review 3. Lymphocyte homing into the gut.

Authors: S Jalkanen
Journal: Springer Semin Immunopathol Date: 1990

9. B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis.

Authors: Rajesh K Sinha; Chung Park; Il-Young Hwang; Michael D Davis; John H Kehrl
Journal: Immunity Date: 2009-02-19 Impact factor: 31.745

10. The appearance of fluorescein-labelled lymphocytes in lymph following in vitro or in vivo labelling: the route of lymphocyte recirculation through mesenteric lymph nodes.

Authors: G W Chin; N P Cahill
Journal: Immunology Date: 1984-06 Impact factor: 7.397