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Literature DB >> 14319399

LEUKOCYTES AND INTERFERON IN THE HOST RESPONSE TO VIRAL INFECTIONS. I. MOUSE LEUKOCYTES AND LEUKOCYTE-PRODUCED INTERFERON IN VACCINIA VIRUS INFECTION IN VITRO.

Abstract

1. Investigation of the role of leukocytes in vaccinia virus infection is reported in an in vitro model, in the absence of an immune response. 2. Mouse leukocytes were shown to be capable of inhibiting the progression of vaccinia virus infection in primary mouse embryo fibroblast cultures. The degree of protection varied from slowing of spread of infection to complete control of the infection with eventual elimination of detectable virus and recovery of the culture. 3. Interferon production by leukocytes is thought to be an important factor in the observed protective effect.

Entities: Disease Species

Keywords: CHICK EMBRYO; EXPERIMENTAL LAB STUDY; FIBROBLASTS; INTERFERON; LEUKOCYTES; MICE; MODELS, THEORETICAL; PHAGOCYTOSIS; TISSUE CULTURE; TRYPSIN; VACCINIA VIRUS; VIRUS CULTIVATION

Mesh：

Substances：
Interferons
Trypsin

Year: 1965 PMID： 14319399 PMCID： PMC2138021 DOI： 10.1084/jem.121.6.1001

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

23 in total

1. PURIFIED INTERFERONS: PHYSICAL PROPERTIES AND SPECIES SPECIFICITY.

Authors: T C MERIGAN
Journal: Science Date: 1964-08-21 Impact factor: 47.728

2. INTRACYTOPLASMIC VIRUS CRYSTAL FORMATION AND OTHER ALLTERATIONS IN POLYMORPHONUCLEAR LEUKOCYTES IN MOUSE POLIOENCEPHALITIS (MM STRAIN).

Authors: E NELSON; H HAGER; E KOVACS
Journal: Am J Pathol Date: 1964-01 Impact factor: 4.307

3. Isolation of measles virus from the washed leucocytic fraction of blood.

Authors: I GRESSER; C CHANY
Journal: Proc Soc Exp Biol Med Date: 1963-07

4. Alteration of cellular resistance to Sindbis virus in mixed cultures of human cells attributable to interferon.

Authors: I GRESSER; J F ENDERS
Journal: Virology Date: 1962-04 Impact factor: 3.616

5. Study of the mechanism of innate resistance to virus infection.

Authors: G T GOODMAN; H KOPROWSKI
Journal: J Cell Comp Physiol Date: 1962-06

6. Blood clearance of P32-labeled vesicular stomatitis and Newcastle disease viruses by the reticuloendothelial system in mice.

Authors: K T BRUNNER; D HUREZ; R T McCLUSKEY; B BENACERRAF
Journal: J Immunol Date: 1960-07 Impact factor: 5.422

7. Phagocytosis of influenza virus. I. In vitro observations.

Authors: A V BOAND; J E KEMPF; R J HANSON
Journal: J Immunol Date: 1957-11 Impact factor: 5.422

8. The role of interferon in vaccinia virus infection of mouse embryo tissue culture.

Authors: L A GLASGOW; K HABEL
Journal: J Exp Med Date: 1962-03-01 Impact factor: 14.307

9. THE RECOVERY OF VACCINE VIRUS AFTER NEUTRALIZATION WITH IMMUNE SERUM.

Authors: P H Long; P K Olitskly
Journal: J Exp Med Date: 1930-01-31 Impact factor: 14.307

10. THE FATE OF VACCINIA VIRUS ON CULTIVATION IN VITRO WITH KUPFFER CELLS (RETICULO-ENDOTHELIAL CELLS).

Authors: J W Beard; P Rous
Journal: J Exp Med Date: 1938-05-31 Impact factor: 14.307

14 in total

1. Production of interferon by alveolar macrophages.

Authors: J D Acton; Q N Myrvik
Journal: J Bacteriol Date: 1966-06 Impact factor: 3.490

2. Leukocytes and interferon in the host response to viral infections. II. Enhanced interferon response of leukocytes from immune animals.

Authors: L A Glasgow
Journal: J Bacteriol Date: 1966-06 Impact factor: 3.490

3. Enhancement of resistance to murine osteogenic sarcoma in vivo by an extract of Brucella abortus (Bru-Pel): association with activation of reticuloendothelial system macrophages.

Authors: L A Glasgow; J L Crane; C J Schleupner; E R Kern; J S Youngner; D S Feingold
Journal: Infect Immun Date: 1979-01 Impact factor: 3.441

4. Selective increase in lymphocyte interferon response to vaccinia antigen after revaccination.

Authors: L B Epstein; D A Stevens; T C Merigan
Journal: Proc Natl Acad Sci U S A Date: 1972-09 Impact factor: 11.205

5. Interactions between calf alveolar macrophages and parainfluenza-3 virus.

Authors: M Probert; E J Stott; L H Thomas
Journal: Infect Immun Date: 1977-02 Impact factor: 3.441

Review 6. Interferon: a changing picture.

Authors: R P Larke
Journal: Can Med Assoc J Date: 1966-01-01 Impact factor: 8.262

7. Interferon and host resistance to Rauscher virus-induced leukemia.

Authors: L A Glasgow; S B Friedman
Journal: J Virol Date: 1969-02 Impact factor: 5.103

Review 8. Poxvirus pathogenesis.

Authors: R M Buller; G J Palumbo
Journal: Microbiol Rev Date: 1991-03

9. Interferon in the cerebrospinal fluid of children with central nervous system disorders.

Authors: R P Larke
Journal: Can Med Assoc J Date: 1967-01-07 Impact factor: 8.262

10. Virus replication and high-titered interferon production in human leukocyte cultures inoculated with Newcastle disease virus.

Authors: E F Wheelock
Journal: J Bacteriol Date: 1966-11 Impact factor: 3.490