Literature DB >> 1431274

Transplacental transfer of schistosomal antigens and antibodies.

S A Romia1, A E Handoussa, S A Youseff, M M el Zayat.   

Abstract

Circulating S. mansoni soluble antigens (CSA) and antibodies (CAB) were investigated in sera of 32 S. mansoni-infected pregnant mothers, their 32 newborns and 26 non-pregnant infected women. CSA levels in pregnant mothers and their newborns were significantly higher than in the 3rd group. Also, a significant positive correlation was detected between the CSA levels in sera from infected mothers and the cord blood of their newborns proving the transplacental transfer of these antigens. On the other hand, CAB levels were significantly higher in the 3rd group than in the mothers and their newborns and this could be explained by the immune complexes formation. No schistosome eggs or worms were detected in placentas and the possibility of congenital schistosomiasis was eliminated.

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Year:  1992        PMID: 1431274

Source DB:  PubMed          Journal:  J Egypt Soc Parasitol        ISSN: 1110-0583


  6 in total

1.  Maternal Schistosomiasis japonica is associated with maternal, placental, and fetal inflammation.

Authors:  Jonathan D Kurtis; Ashley Higashi; Hai-Wei Wu; Fusun Gundogan; Emily A McDonald; Surrendra Sharma; Sunthorn PondTor; Blanca Jarilla; Marriane Joy Sagliba; Analisa Gonzal; Remigio Olveda; Luz Acosta; Jennifer F Friedman
Journal:  Infect Immun       Date:  2010-12-13       Impact factor: 3.441

2.  Association of in utero sensitization to Schistosoma haematobium with enhanced cord blood IgE and increased frequencies of CD5- B cells in African newborns.

Authors:  Larsen S Seydel; Annika Petelski; Govert J van Dam; Desiree van der Kleij; Yvonne C M Kruize-Hoeksma; Adrian J F Luty; Maria Yazdanbakhsh; Peter G Kremsner
Journal:  Am J Trop Med Hyg       Date:  2012-04       Impact factor: 2.345

3.  Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial.

Authors:  Robert Tweyongyere; Patrice A Mawa; Macklyn Kihembo; Frances M Jones; Emily L Webb; Stephen Cose; David W Dunne; Birgitte J Vennervald; Alison M Elliott
Journal:  BMC Infect Dis       Date:  2011-09-02       Impact factor: 3.090

4.  Maternal infection with Schistosoma japonicum induces a profibrotic response in neonates.

Authors:  Emily A McDonald; Ling Cheng; Blanca Jarilla; Marianne J Sagliba; Annaliza Gonzal; Amabelle J Amoylen; Remigio Olveda; Luz Acosta; David Baylink; Eric S White; Jennifer F Friedman; Jonathan D Kurtis
Journal:  Infect Immun       Date:  2013-10-28       Impact factor: 3.441

5.  Schistosoma japonicum soluble egg antigens attenuate invasion in a first trimester human placental trophoblast model.

Authors:  Emily A McDonald; Jennifer F Friedman; Surendra Sharma; Luz Acosta; Sunthorn Pond-Tor; Ling Cheng; Eric S White; Jonathan D Kurtis
Journal:  PLoS Negl Trop Dis       Date:  2013-06-06

Review 6.  Pregnancy and helminth infections.

Authors:  H Mpairwe; R Tweyongyere; A Elliott
Journal:  Parasite Immunol       Date:  2014-08       Impact factor: 2.280

  6 in total

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