Literature DB >> 1430958

Intra-articular corticosteroid reduces joint stiffness after an experimental periarticular fracture.

R S Namba1, J M Kabo, F J Dorey, R A Meals.   

Abstract

Early care after surgery or trauma to the extremities often includes a period of immobilization. The resultant joint stiffness may require extensive rehabilitation and may permanently limit function of the limb. Posttraumatic joint stiffness is particularly vexing in the small joints. In an experimental model, we tested the effects of intra-articular corticosteroid injections on stiffness in a joint at risk of posttraumatic joint stiffness. Triamcinolone was injected into ankle joints of rabbits after distal tibial fractures. Three weeks after injury, joint stiffness increased 34% in ankles injected with the steroid. Stiffness in ankles injected with saline solution and in ankles treated with no injection increased 133% and 224%, respectively. Limb swelling and tibial torsional strength to failure were not significantly affected by either of the treatments.

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Year:  1992        PMID: 1430958     DOI: 10.1016/s0363-5023(09)91083-8

Source DB:  PubMed          Journal:  J Hand Surg Am        ISSN: 0363-5023            Impact factor:   2.230


  3 in total

1.  Joint capsule matrix turnover in a rabbit model of chronic joint contractures: Correlation with human contractures.

Authors:  Kevin A Hildebrand; Mei Zhang; David A Hart
Journal:  J Orthop Res       Date:  2006-05       Impact factor: 3.494

2.  A new method to measure post-traumatic joint contractures in the rabbit knee.

Authors:  Kevin A Hildebrand; Michael Holmberg; Nigel Shrive
Journal:  J Biomech Eng       Date:  2003-12       Impact factor: 2.097

3.  Effects of losartan and atorvastatin on the development of early posttraumatic joint stiffness in a rat model.

Authors:  Andreas Baranowski; Ludwig Schlemmer; Katharina Förster; Ekaterina Slotina; Tim Mickan; Sebastian Truffel; Anja Klein; Stefan G Mattyasovszky; Alexander Hofmann; Ulrike Ritz; Pol M Rommens
Journal:  Drug Des Devel Ther       Date:  2019-07-30       Impact factor: 4.162

  3 in total

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