Literature DB >> 1430549

Iontophoretic administration of lidocaine anesthesia in office practice. An appraisal.

J M Maloney1, J L Bezzant, R L Stephen, T J Petelenz.   

Abstract

BACKGROUND: Obtaining anesthesia for dermatologic, office-based surgeries often involves the pain of needle stick and burning upon injection of local anesthetic agents. No truly effective method for obtaining painless anesthesia is well accepted in the United States.
OBJECTIVE: A study was carried out using iontophoresis of lidocaine with epinephrine to determine the practicality of this method of delivering local anesthesia prior to invasive procedures in dermatology offices.
METHODS: A two-center, open-label study was undertaken using iontophoretic administration of 4% lidocaine with epinephrine 1:50,000 before painful procedures occurring in the dermatologists' office.
RESULTS: Ninety-four procedures in 64 patients were evaluated. Both patients and physicians recorded 51% of procedures as painless, 36% as minor (partial), and 14% causing moderate to severe pain. Iontophoretic local anesthesia was 80 to 100% effective for pain relief for injections, abrasions, laser surgery, and cautery; it was significantly less effective in effecting pain relief for dermal excisions.
CONCLUSIONS: Iontophoretic administration of anesthesia is a useful adjunct to the armamentarium of dermatologists performing surgical procedures in their office.

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Year:  1992        PMID: 1430549     DOI: 10.1111/j.1524-4725.1992.tb02764.x

Source DB:  PubMed          Journal:  J Dermatol Surg Oncol        ISSN: 0148-0812


  6 in total

Review 1.  Transdermal iontophoresis. Pharmacokinetic considerations.

Authors:  P Singh; H I Maibach
Journal:  Clin Pharmacokinet       Date:  1994-05       Impact factor: 6.447

Review 2.  Drug management in skin surgery.

Authors:  C Lawrence
Journal:  Drugs       Date:  1996-12       Impact factor: 9.546

3.  Percutaneous dermal drug delivery for local pain control.

Authors:  Sujatha Tadicherla; Brian Berman
Journal:  Ther Clin Risk Manag       Date:  2006-03       Impact factor: 2.423

4.  Clinical pain evaluation with intraoral vibration device during local anesthetic injections.

Authors:  Amin Nasehi; Savita Bhardwaj; Abhay-Taranath Kamath; Srikanth Gadicherla; Kalyana-Chakravarty Pentapati
Journal:  J Clin Exp Dent       Date:  2015-02-01

5.  The effects and side effects of lidocaine tetracaine peel off on laser-assisted hair removal.

Authors:  Ali Asilian; Zabihollah Shahmoradi; Rabie Mazloomi; Mohammad Ali Nilforoushzadeh
Journal:  Adv Biomed Res       Date:  2014-03-31

6.  Using a Vibration Device to Ease Pain During Facial Needling and Injection.

Authors:  Hiroaki Kuwahara; Rei Ogawa
Journal:  Eplasty       Date:  2016-02-04
  6 in total

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