Literature DB >> 1430353

Serum androgens and depression in women with facial hirsutism.

L H Shulman1, L DeRogatis, R Spielvogel, J L Miller, L I Rose.   

Abstract

BACKGROUND: Studies on the psychopathologic aspects of hirsutism are sparse. Attempts to correlate these aspects with either the extent of the facial hirsutism and/or circulating serum androgens are virtually nonexistent. This study evaluates the psychopathologic aspects of hirsutism and correlates these findings with the extent of the facial hirsutism as well as with the circulating serum androgens.
OBJECTIVE: Our purpose was to assess the psychopathologic aspects of facial hirsutism and to determine whether any correlation exists between these findings and either the extent of the facial hirsutism or the circulating serum androgens.
METHODS: Twenty consecutive women with facial hirsutism were studied by administration of psychologic tests (DeRogatis Symptom Inventory and the Affects Balance Scale). The results of these tests were correlated with the grade of facial hirsutism as well as serum levels of total testosterone (T), biologically active testosterone (BT), free testosterone (FT), dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and androstenedione (A-dione).
RESULTS: Significant levels of depression were found. No correlation was found between the psychopathologic measurements and the extent of facial hirsutism or serum levels of T, DHEA, DHEA-S, and A-dione. Significant correlations were found between depression and serum levels of FT and BT.
CONCLUSION: There is an increased incidence of depression in facially hirsute women and this correlates with their circulating active testosterone levels and not with the extent of their facial hirsutism.

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Year:  1992        PMID: 1430353     DOI: 10.1016/0190-9622(92)70166-d

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  9 in total

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Journal:  Noro Psikiyatr Ars       Date:  2014-12-01       Impact factor: 1.339

2.  Association of testosterone levels and future suicide attempts in females with bipolar disorder.

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7.  Clinical Characteristics of Hyperandrogenism Include Hirsutism, Polycystic Ovary Syndrome, and Acne: Association with Psychiatric Disease in Women -A Nationwide Population-Based Cohort Study in Taiwan.

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8.  Psychological distress in women with polycystic ovary syndrome from imam khomeini hospital, tehran.

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9.  Stressful life events and psychosocial correlates of pediatric inflammatory bowel disease activity.

Authors:  George Giannakopoulos; George Chouliaras; Daphne Margoni; Sophia Korlou; Vassiliki Hantzara; Ioanna Panayotou; Eleftheria Roma; Magda Liakopoulou; Dimitris C Anagnostopoulos
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  9 in total

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