| Literature DB >> 14301897 |
Abstract
Degenerated brain tissue obtained from a deceased patient who had progressive multifocal leukoencephalopathy had been fixed in formalin prior to processing for electron microscopy. In ultrathin sections virus-like particles resembling papova virions were frequently observed in glial nuclei. Correlation with light-microscopy findings suggests that demyelination resulted from the cytocidal effect of the virus on oligodendroglia.Entities:
Keywords: DEMYELINATION; MICROSCOPY, ELECTRON; NEUROGLIA; PAPOVAVIRUS; PATHOLOGY; VIRUS DISEASES
Mesh:
Year: 1965 PMID: 14301897 DOI: 10.1126/science.148.3676.1477
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728