| Literature DB >> 14292988 |
Abstract
Rosenberg, Eugene (University of California, Los Angeles), and Paul Holmes. Oxidation of secondary alcohols by extracts of a Corynebacterium. J. Bacteriol. 89:1212-1216. 1965.-A Corynebacterium was isolated from soil by use of the enrichment culture technique. This Corynebacterium oxidized and grew on the chemically synthesized secondary alcohol, 3-tetrahydrofuranol. Extracts of this organism contained at least two different nicotinamide adenine dinucleotide-requiring soluble secondary alcohol dehydrogenases. These enzymes were distinguished by the relative rates at which they oxidized thymidylic acid and 3-tetrahydrofuranol. In addition to their substrate specificity, the two enzymes differed in pH optima and thermal stability. Also, the 3-tetrahydrofuranol dehydrogenase was induced by 3-tetrahydrofuranol, whereas the thymidylic acid dehydrogenase was constitutive.Entities:
Keywords: ALCOHOL OXIDOREDUCTASES; ALCOHOLS; CORYNEBACTERIUM; EXPERIMENTAL LAB STUDY; FURANS; HYDROGEN-ION CONCENTRATION; NAD; NUCLEOTIDES; OXIDATION-REDUCTION; TEMPERATURE
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Year: 1965 PMID: 14292988 PMCID: PMC277630 DOI: 10.1128/jb.89.5.1212-1216.1965
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490