Literature DB >> 14290076

RESULTS OF THE STUDY OF TYPHOID VACCINES IN FOUR CONTROLLED FIELD TRIALS IN THE USSR.

L B HEJFEC.   

Abstract

In field trials of typhoid vaccine in the USSR, a comparison was made of the effectiveness of chemical, heat-killed, and alcoholized vaccines. All of them conferred protection if administered in sufficient dosage, and variations in effectiveness could usually be traced to size of dosage. The heat-killed vaccine, however, appeared to be significantly more effective than the others. The immunological history of a vaccinated person apparently had no essential influence on the effectiveness of a vaccine, and the data indicated that two doses of the vaccine conferred no greater protection than one.

Entities:  

Keywords:  ADOLESCENCE; STATISTICS; TYPHOID-PARATYPHOID VACCINES; USSR; VACCINATION

Mesh：

Substances：

Year:  1965        PMID： 14290076      PMCID： PMC2555188     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN： 0042-9686            Impact factor:   9.408


  2 in total

1.  Large-scale field trials of active immunizing agents; with special reference to vaccination against pertussis.

Authors:  W C COCKBURN
Journal:  Bull World Health Organ       Date:  1955       Impact factor: 9.408

2.  The clinical trial.

Authors:  A B HILL
Journal:  Br Med Bull       Date:  1951       Impact factor: 4.291
  2 in total
  8 in total

1.  THE PRESENT STATUS OF FIELD AND LABORATORY STUDIES OF TYPHOID AND PARATYPHOID VACCINES WITH SPECIAL REFERENCE TO STUDIES SPONSORED BY WORLD HEALTH ORGANIZATION.

Authors:  B CVJETANOVIC; K UEMURA
Journal:  Bull World Health Organ       Date:  1965       Impact factor: 9.408

2.  A controlled field trial to evaluate the protective capacity of a single dose of acetone-killed agar-grown and heat-killed broth-grown typhoid vaccines.

Authors:  L B Hejfec; L A Levina; M L Kuz'minova; A M Slavina; A K Drozd; I A Tonojan; L I Koenman; N E Levites; L A Abidov; A Z Abidov; L F Goncarova
Journal:  Bull World Health Organ       Date:  1969       Impact factor: 9.408

3.  The sensitizing effect of various typhoid vaccines as revealed under experimental conditions.

Authors:  E N Melikova; S V Lesnjak
Journal:  Bull World Health Organ       Date:  1969       Impact factor: 9.408

4.  A controlled field trial and laboratory study of five typhoid vaccines in the USSR.

Authors:  L B Hejfec; L V Salmin; M Z Lejtman; M L Kuz'minova; A V Vasil'eva; L A Levina; T G Bencianova; E A Pavlova; A A Antonova
Journal:  Bull World Health Organ       Date:  1966       Impact factor: 9.408

5.  Holiday typhoid and T.A.B.

Authors: 
Journal:  Br Med J       Date:  1970-02-28

Review 6.  Part I. Analysis of data gaps pertaining to Salmonella enterica serotype Typhi infections in low and medium human development index countries, 1984-2005.

Authors:  J A Crump; P K Ram; S K Gupta; M A Miller; E D Mintz
Journal:  Epidemiol Infect       Date:  2007-08-09       Impact factor: 2.451

Review 7.  Vaccines for preventing typhoid fever.

Authors:  Rachael Milligan; Mical Paul; Marty Richardson; Ami Neuberger
Journal:  Cochrane Database Syst Rev       Date:  2018-05-31

8.  Generating the Evidence for Typhoid Vaccine Introduction: Considerations for Global Disease Burden Estimates and Vaccine Testing Through Human Challenge.

Authors:  James E Meiring; Alberto Giubilini; Julian Savulescu; Virginia E Pitzer; Andrew J Pollard
Journal:  Clin Infect Dis       Date:  2019-10-15       Impact factor: 9.079
  8 in total

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