Literature DB >> 14289614

POLYMORPHISM OF HUMAN LACTATE DEHYDROGENASE ISOZYMES.

E S VESELL.   

Abstract

Of 1200 individuals screened, four had variant erythrocyte lactate dehydrogenases. Three of these, identical electrophoretically to the Mem-1 described by Kraus and Neely, were heterozygous variants involving the a-locus. The fourth, involving the b-locus, appears to be the first example in man of a homozygous variant.

Entities:  

Keywords:  CAUCASIAN RACE; ELECTROPHORESIS; ERYTHROCYTES; GENETICS, HUMAN; LACTATE DEHYDROGENASE; NEGROES

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Year:  1965        PMID： 14289614     DOI： 10.1126/science.148.3673.1103

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  8 in total

Review 1.  From human genetics and genomics to pharmacogenetics and pharmacogenomics: past lessons, future directions.

Authors:  Daniel W Nebert; Ge Zhang; Elliot S Vesell
Journal:  Drug Metab Rev       Date:  2008       Impact factor: 4.518

2.  A genetically controlled lactate dehydrogenase variant at the B locus in mink.

Authors:  R Saison
Journal:  Biochem Genet       Date:  1971-02       Impact factor: 1.890

3.  [Studies on the pattern and distribution of enzymes in the nucous membrane of the gastrointestinal tract. 3. Electrophoretic characterization of enzymes of the mucous membrane of the stomach, small intestine, and rectum occurring in multiple forms and comparative serum analyses].

Authors:  U E Klein; H C Drube; H T Hansen; H Mielke
Journal:  Klin Wochenschr       Date:  1967-03-01

4.  LDH Calcutta-1: a mutation of the B subunit of human lactate dehydrogenase.

Authors:  A E Cutten
Journal:  Biochem Genet       Date:  1981-08       Impact factor: 1.890

5.  [Comparison of the activities of various serum enzymes in twins].

Authors:  W Schloot; J D Murken; H W Goedde
Journal:  Humangenetik       Date:  1966

6.  [Further tests on the phylogenetics of pseudocholinesterases].

Authors:  H W Goedde; R A Hofmann; W Fuss; K Omoto
Journal:  Humangenetik       Date:  1966

7.  [The electrophoretic separation of lactic acid dehydrogenase isoenzyme, non specific esterases and alkaline phosphatases from human blood cells].

Authors:  U E Klein; H Löffler; E Leuckfeld
Journal:  Klin Wochenschr       Date:  1966-06-01

8.  Defining the locus of origin of a genetically determined electrophoretic variant of a multilocus enzyme system; the Calcutta-1 of human LDH system is a B-locus variant.

Authors:  E Herbschleb-Voogt; P Meera Khan
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132
  8 in total

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