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Literature DB >> 14287601

SPECIFICITY OF MACROGLOBULIN ANTIBODY SYNTHESIZED BY THE NORMAL HUMAN FETUS.

Abstract

The umbilical cord blood of 47 out of 54 normal human infants contains hemagglutinating activity directed toward cells coated with a type-L Bence-Jones protein. This hemagglutinating material, in some instances, is present in cord blood in the absence of such activity in the maternal blood. Ultracentrifugation of cord serum in a sucrose gradient shows that the activity is associated with the macroglobulin fractions.

Entities: Chemical Species

Keywords: ANTIBODY FORMATION; BENCE JONES PROTEIN; FETUS; HEMAGGLUTINATION; MACROGLOBULINS; PHYSIOLOGY; PREGNANCY; ULTRACENTRIFUGATION; UMBILICAL CORD

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Substances：

Year: 1965 PMID： 14287601 DOI： 10.1126/science.148.3677.1591

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

6 in total

6. Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. II. Determination of frequency and characteristics of idiotypic T and B lymphocytes in normal rats using direct visualization.

Authors: H Binz; H Wigzell
Journal: J Exp Med Date: 1975-11-01 Impact factor: 14.307

6 in total

SPECIFICITY OF MACROGLOBULIN ANTIBODY SYNTHESIZED BY THE NORMAL HUMAN FETUS.

1. Lymphocytes with membrane-bound immunoglobulin (B-lymphocytes) in new-born babies.

2. Naturally-occurring macroglobulin antibody of foetal origin in the normal human newborn.

3. Distribution of malarial antibody in maternal and cord sera.

4. Anti-IgG agglutinins in idiopathic respiratory distress syndrome of the newborn.

Review 5. Immunological diseases and pregnancy.

6. Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. II. Determination of frequency and characteristics of idiotypic T and B lymphocytes in normal rats using direct visualization.