| Literature DB >> 14281723 |
Abstract
Amino acids of the aspartic acid family are synthesized in bacteria through a multistep branched pathway. In the photosynthetic bacterium Rhodopseudomonas capsulatus, the enzyme that catalyzes the first step is specifically inhibited by a combination of two end-product amino acids. Evidence is presented for operation of this kind of "concerted" feedback control as a regulatory device in growing cells.Entities:
Keywords: ALCOHOL OXIDOREDUCTASES; AMINO ACID METABOLISM; ENZYMES; EXPERIMENTAL LAB STUDY; FEEDBACK; LYSINE; METHIONINE; PHOSPHOTRANSFERASES; RHODOPSEUDOMONAS; THREONINE
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Year: 1965 PMID： 14281723 DOI： 10.1126/science.148.3675.1351
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728