Literature DB >> 1428121

Enzymatic activity and immunoreactivity of extracellular phospholipase A2 in inflammatory synovial fluids.

W Pruzanski1, K Scott, G Smith, I Rajkovic, E Stefanski, P Vadas.   

Abstract

Synovial fluid PLA2 concentration was measured by an ELISA technique using monoclonal antibodies raised against human recombinant "synovial-type" group II phospholipase A2. This ELISA was specific for synovial-type PLA2 and did not detect pancreatic (group I) PLA2. In all synovial fluids examined, including rheumatoid, osteoarthritic, psoriatic, and gouty fluids, synovial fluid PLA2 enzyme activity significantly correlated with PLA2 immunoreactivity (P < 0.001). Within the limits of the ELISA technique, there was no evidence for the presence of specific or nonspecific modulation of PLA2 activity by either putative PLA2 activating or inhibitory proteins.

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Year:  1992        PMID： 1428121     DOI： 10.1007/bf00918971

Source DB:  PubMed          Journal:  Inflammation        ISSN： 0360-3997            Impact factor:   4.092


  23 in total

Review 1.  Role of secretory phospholipases A2 in the pathobiology of disease.

Authors:  P Vadas; W Pruzanski
Journal:  Lab Invest       Date:  1986-10       Impact factor: 5.662

2.  Serum phospholipase A2 correlates with disease activity in rheumatoid arthritis.

Authors:  W Pruzanski; E C Keystone; B Sternby; C Bombardier; K M Snow; P Vadas
Journal:  J Rheumatol       Date:  1988-09       Impact factor: 4.666

Review 3.  Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids.

Authors:  R J Flower
Journal:  Br J Pharmacol       Date:  1988-08       Impact factor: 8.739

4.  Identification and isolation of a phospholipase A2 activating protein in human rheumatoid arthritis synovial fluid: induction of eicosanoid synthesis and an inflammatory response in joints injected in vivo.

Authors:  J S Bomalaski; M Fallon; R A Turner; S T Crooke; P C Meunier; M A Clark
Journal:  J Lab Clin Med       Date:  1990-12

5.  Pancreatic phospholipase A2: isolation of the human gene and cDNAs from porcine pancreas and human lung.

Authors:  J J Seilhamer; T L Randall; M Yamanaka; L K Johnson
Journal:  DNA       Date:  1986-12

6.  The proinflammatory effect of intra-articular injection of soluble human and venom phospholipase A2.

Authors:  P Vadas; W Pruzanski; J Kim; V Fornasier
Journal:  Am J Pathol       Date:  1989-04       Impact factor: 4.307

7.  Measurement of human phospholipase A2 in arthritis plasma using a newly developed sandwich ELISA.

Authors:  G M Smith; R L Ward; L McGuigan; I A Rajkovic; K F Scott
Journal:  Br J Rheumatol       Date:  1992-03

8.  Multiple forms of phospholipase A2 in arthritic synovial fluid.

Authors:  J J Seilhamer; S Plant; W Pruzanski; J Schilling; E Stefanski; P Vadas; L K Johnson
Journal:  J Biochem       Date:  1989-07       Impact factor: 3.387

9.  Influence of plasma proteins on activity of proinflammatory enzyme phospholipase A2.

Authors:  P Vadas; E Stefanski; W Pruzanski
Journal:  Inflammation       Date:  1986-06       Impact factor: 4.092

10.  Purification of a soluble phospholipase A2 from synovial fluid in rheumatoid arthritis.

Authors:  E Stefanski; W Pruzanski; B Sternby; P Vadas
Journal:  J Biochem       Date:  1986-11       Impact factor: 3.387
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  11 in total

1.  Serum amyloid A protein enhances the activity of secretory non-pancreatic phospholipase A2.

Authors:  W Pruzanski; F C de Beer; M C de Beer; E Stefanski; P Vadas
Journal:  Biochem J       Date:  1995-07-15       Impact factor: 3.857

2.  Increased expression of human type IIa secretory phospholipase A2 antigen in arthritic synovium.

Authors:  O S Jamal; P G Conaghan; A M Cunningham; P M Brooks; V F Munro; K F Scott
Journal:  Ann Rheum Dis       Date:  1998-09       Impact factor: 19.103

3.  Increased group II phospholipase A2 in colonic mucosa of patients with Crohn's disease and ulcerative colitis.

Authors:  T Minami; H Tojo; Y Shinomura; Y Matsuzawa; M Okamoto
Journal:  Gut       Date:  1994-11       Impact factor: 23.059

4.  Synergy between 15-lipoxygenase and secreted PLA2 promotes inflammation by formation of TLR4 agonists from extracellular vesicles.

Authors:  Van Thai Ha; Duško Lainšček; Bernd Gesslbauer; Eva Jarc-Jovičić; Tuulia Hyötyläinen; Nejc Ilc; Katja Lakota; Matija Tomšič; Fons A J van de Loo; Valery Bochkov; Toni Petan; Roman Jerala; Mateja Manček-Keber
Journal:  Proc Natl Acad Sci U S A       Date:  2020-09-24       Impact factor: 11.205

5.  sPLA2-IIa is an inflammatory mediator when the ocular surface is compromised.

Authors:  Dongmei Chen; Yi Wei; Xiaohong Li; Seth Epstein; J Mario Wolosin; Penny Asbell
Journal:  Exp Eye Res       Date:  2008-12-16       Impact factor: 3.467

6.  Sequence specific inhibition of human type II phospholipase A2 enzyme activity by phosphorothioate oligonucleotides.

Authors:  C F Bennett; M Y Chiang; L Wilson-Lingardo; J R Wyatt
Journal:  Nucleic Acids Res       Date:  1994-08-11       Impact factor: 16.971

7.  A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.

Authors:  Eric Boilard; Ying Lai; Katherine Larabee; Barbara Balestrieri; Farideh Ghomashchi; Daisuke Fujioka; Reuben Gobezie; Jonathan S Coblyn; Michael E Weinblatt; Elena M Massarotti; Thomas S Thornhill; Maziar Divangahi; Heinz Remold; Gérard Lambeau; Michael H Gelb; Jonathan P Arm; David M Lee
Journal:  EMBO Mol Med       Date:  2010-05       Impact factor: 12.137

8.  Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions.

Authors:  D F Cardoso; M Lopes-Ferreira; E L Faquim-Mauro; M S Macedo; S H Farsky
Journal:  Mediators Inflamm       Date:  2001-06       Impact factor: 4.711

9.  Quantitation of human tissue and immune cell type II 14 kDa phospholipase A(2) by enzyme immunoassay.

Authors:  B J Bolognese; S D Holmes; L J McMillan; K F Kaiser; L A Marshall
Journal:  Inflammopharmacology       Date:  1997       Impact factor: 5.093

Review 10.  Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A2.

Authors:  Ryung Rae Kim; Zheng Chen; Timothy J Mann; Karine Bastard; Kieran F Scott; W Bret Church
Journal:  Molecules       Date:  2020-09-28       Impact factor: 4.411
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