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Literature DB >> 14281103

FLUORINATED PYRIMIDINES. XXIV. IN VIVO METABOLISM OF 5-TRIFLUOROMETHYLURACIL-2-C-14 AND 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE-2-C-14.

C HEIDELBERGER, J BOOHAR, B KAMPSCHROER.

Abstract

Entities: Chemical

Keywords: CARBON ISOTOPES; DEOXYURIDINE; DNA; EXPERIMENTAL LAB STUDY; FLUORINE; METABOLISM; MICE; NEOPLASMS, EXPERIMENTAL; NUCLEOSIDES; RADIOMETRY; URACIL

Mesh：

Substances：

Year: 1965 PMID： 14281103

Source DB: PubMed Journal: Cancer Res ISSN： 0008-5472 Impact factor: 12.701

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8 in total

Review 1. TAS-102, a novel antitumor agent: a review of the mechanism of action.

Authors: Heinz-Josef Lenz; Sebastian Stintzing; Fotios Loupakis
Journal: Cancer Treat Rev Date: 2015-06-06 Impact factor: 12.111

2. Human mass balance study of TAS-102 using (14)C analyzed by accelerator mass spectrometry.

Authors: James J Lee; Jabed Seraj; Kenichiro Yoshida; Hirokazu Mizuguchi; Sandra Strychor; Jillian Fiejdasz; Tyeler Faulkner; Robert A Parise; Patrick Fawcett; Laura Pollice; Scott Mason; Jeremy Hague; Marie Croft; James Nugteren; Charles Tedder; Weijing Sun; Edward Chu; Jan Hendrik Beumer
Journal: Cancer Chemother Pharmacol Date: 2016-01-19 Impact factor: 3.333

3. Effects of 5-fluoro-2'-deoxyuridine on bacterial growth. Its use for DNA labelling.

Authors: T Reuvers; D García-Pineda; C A Dávila
Journal: Antonie Van Leeuwenhoek Date: 1973 Impact factor: 2.271

Review 4. The Role of Fluoropirimidines in Gastrointestinal Tumours: from the Bench to the Bed.

Authors: Jorge Hernando-Cubero; Ignacio Matos-García; Vicente Alonso-Orduña; Jaume Capdevila
Journal: J Gastrointest Cancer Date: 2017-06

5. Potentiation of the antitumor activity of 5-trifluoromethyl-2'-deoxyuridine by the use of depot forms of the parent compound.

Authors: S Takeda; K Wierzba; J Yamashita; H Matsumoto; H Satake; Y Yamada; N Unemi; Y Wataya; H Hayatsu
Journal: Cancer Chemother Pharmacol Date: 1992 Impact factor: 3.333

FLUORINATED PYRIMIDINES. XXIV. IN VIVO METABOLISM OF 5-TRIFLUOROMETHYLURACIL-2-C-14 AND 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE-2-C-14.

Review 1. TAS-102, a novel antitumor agent: a review of the mechanism of action.

2. Human mass balance study of TAS-102 using (14)C analyzed by accelerator mass spectrometry.

3. Effects of 5-fluoro-2'-deoxyuridine on bacterial growth. Its use for DNA labelling.

Review 4. The Role of Fluoropirimidines in Gastrointestinal Tumours: from the Bench to the Bed.

5. Potentiation of the antitumor activity of 5-trifluoromethyl-2'-deoxyuridine by the use of depot forms of the parent compound.

Review 6. Therapeutic potential of TAS-102 in the treatment of gastrointestinal malignancies.

7. Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors.

Review 8. Emerging combination therapies for metastatic colorectal cancer - impact of trifluridine/tipiracil.