Literature DB >> 14281087

LAETRILE: A STUDY OF ITS PHYSICOCHEMICAL AND BIOCHEMICAL PROPERTIES.

L LEVI, W N FRENCH, I J BICKIS, I W HENDERSON.   

Abstract

A study was made of the composition and biochemical behaviour of the drug, Laetrile, distributed for clinical trial in the United States and Canada. It was established that the Canadian and the American product are different pharmaceutical formulations, displaying different physicochemical and biochemical properties. The investigation demonstrated, furthermore, that neither preparation can be considered as a palliative in cancer therapy on the basis of the biological rationale advanced by their manufacturers.

Entities:  

Keywords:  ANTINEOPLASTIC AGENTS; BIOCHEMISTRY; CYANIDES; DRUG THERAPY; NEOPLASM THERAPY; PALLIATIVE TREATMENT; PHARMACOLOGY

Mesh:

Substances:

Year:  1965        PMID: 14281087      PMCID: PMC1928277     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  1 in total

1.  QUALITY CONTROL OF PHARMACEUTICALS.

Authors:  L LEVI; G C WALKER; L I PUGSLEY
Journal:  Can Med Assoc J       Date:  1964-10-10       Impact factor: 8.262

  1 in total
  4 in total

1.  Subacute laetrile intoxication.

Authors:  R C Barnett; J Pointer; J Nimtz; R Beers
Journal:  West J Med       Date:  1981-02

2.  Public health report. The Laetrile hoax.

Authors:  F B Hodges
Journal:  Calif Med       Date:  1973-06

3.  Deliberate self-poisoning with Laetrile.

Authors:  M Moss; N Khalil; J Gray
Journal:  Can Med Assoc J       Date:  1981-11-15       Impact factor: 8.262

4.  Amygdalin (Laetrile) and prunasin beta-glucosidases: distribution in germ-free rat and in human tumor tissue.

Authors:  J Newmark; R O Brady; P M Grimley; A E Gal; S G Waller; J R Thistlethwaite
Journal:  Proc Natl Acad Sci U S A       Date:  1981-10       Impact factor: 11.205

  4 in total

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