Literature DB >> 14280011

FUNCTIONAL STUDIES OF CULTURED BRAIN TISSUES AS RELATED TO "DEMYELINATIVE DISORDERS".

M B BORNSTEIN, S M CRAIN.   

Abstract

The serums from animals with experimental allergic encephalomyelitis and humans with multiple sclerosis produce, in addition to demyelination, rapid, reversible alterations in complex, evoked bioelectric (synaptic) responses of cultured cerebral cortex and spinal cord tissues of the mouse. The active factors are dependent on complement and are not present in serums from normal animals and humans.

Entities:  

Keywords:  ANIMALS, NEWBORN; BLOOD; BRAIN ELECTROPHYSIOLOGY; CEREBRAL CORTEX; COMPLEMENT; DEMYELINATION; ELECTRIC STIMULATION; ENCEPHALOMYELITIS; ENCEPHALOMYELITIS, ALLERGIC; EXPERIMENTAL LAB STUDY; HYPERSENSITIVITY; MICE; MULTIPLE SCLEROSIS; PHARMACOLOGY; SPINAL CORD; TISSUE CULTURE

Mesh：

Substances：

Year:  1965        PMID： 14280011     DOI： 10.1126/science.148.3674.1242

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  23 in total

Review 1.  Immunology of amyotrophic lateral sclerosis.

Authors:  N R Cashman; M E Gurney; J P Antel
Journal:  Springer Semin Immunopathol       Date:  1985

2.  Experimental allergic encephalomyelitis in the rat: histopathological studies and the effects of sera on adult cerebellar organ cultures.

Authors:  D R Pettit; J A Kiernan
Journal:  Acta Neuropathol       Date:  1974-02-07       Impact factor: 17.088

3.  Gas liquid chromatographic analysis of sphingosine bases in sphingolipids of human normal and multiple sclerosis cerebral white matter.

Authors:  E A Moscatelli; E Isaacson
Journal:  Lipids       Date:  1969-11       Impact factor: 1.880

Review 4.  Immunopathological comparisons between experimental autoimmune encephalomyelitis and multiple sclerosis.

Authors:  I R Mackay; P R Carnegie; A S Coates
Journal:  Clin Exp Immunol       Date:  1973-12       Impact factor: 4.330

5.  Binding of 125 I myelin basic protein by serum and cerebrospinal fluid.

Authors:  V Lennon; I R Mackay
Journal:  Clin Exp Immunol       Date:  1972-08       Impact factor: 4.330

6.  [Organic and functional changes in experimental allergic encephalomyelitis in the rhesus monkey].

Authors:  J Simon; O Simonova
Journal:  Z Neurol       Date:  1971

7.  A histological dose-response effect in guinea-pigs injected with graded amounts of basic protein and peptides from human brain.

Authors:  G S Robson; T A McPherson; I R Mackay
Journal:  Br J Exp Pathol       Date:  1971-08

8.  The effects of canine distemper virus on explant tissue cultures of canine cerebellum.

Authors:  R W Storts; A Koestner; R A Dennis
Journal:  Acta Neuropathol       Date:  1968-07-08       Impact factor: 17.088

Review 9.  [Macromolecular data processing in the central nervous system].

Authors:  F O Schmitt
Journal:  Klin Wochenschr       Date:  1967-09-01

10.  A comparison of the effects of melengestrol acetate with a combination of hydrocortisone acetate and medroxyprogesterone acetate and with other steroids in the treatment of experimental alleric encephalomyelitis in Wistar rats.

Authors:  G A Elliott; A J Gibbons; M E Greig
Journal:  Acta Neuropathol       Date:  1973-01-30       Impact factor: 17.088
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