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Literature DB >> 14280002

NUCLEOTIDE SYNTHESIS UNDER POSSIBLE PRIMITIVE EARTH CONDITIONS.

Abstract

The nucleosides adenosine, guanosine, cytidine, uridine, and thymidine were each heated with inorganic phosphate. Nucleoside monophosphates were formed in appreciable yield. This result has a bearing on the hypothesis of chemical evolution.

Entities: Chemical

Keywords: BIOGENESIS; CARBON ISOTOPES; CHEMISTRY; CHROMATOGRAPHY; ELECTROPHORESIS; EXPERIMENTAL LAB STUDY; NUCLEOSIDES; NUCLEOTIDES; RADIOMETRY; THYMIDINE; URIDINE

Mesh：

Substances：

Year: 1965 PMID： 14280002 DOI： 10.1126/science.148.3674.1221

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

23 in total

1. Adsorption of 5'-AMP and catalytic synthesis of 5'-ADP onto phosphate surfaces: correlation to solid matrix structures.

Authors: A C Tessis; H Salim De Amorim; M Farina; F DeSouza-Barros; A Vieyra
Journal: Orig Life Evol Biosph Date: 1995-08 Impact factor: 1.950

7. The fundamental nature of the genetic code: prebiotic interactions between polynucleotides and polyamino acids or their derivatives.

Authors: C R Woese
Journal: Proc Natl Acad Sci U S A Date: 1968-01 Impact factor: 11.205

8. Prebiotic formation of ADP and ATP from AMP, calcium phosphates and cyanate in aqueous solution.

Authors: Y Yamagata
Journal: Orig Life Evol Biosph Date: 1999-10 Impact factor: 1.950

9. Modulation of adenosine 5'-monophosphate adsorption onto aqueous resident pyrite: potential mechanisms for prebiotic reactions.

Authors: M Pontes-Buarques; A C Tessis; J A Bonapace; M B Monte; G Cortés-Lopez; F De Souza-Barros; A Vieyra
Journal: Orig Life Evol Biosph Date: 2001 Aug-Oct Impact factor: 1.950

10. Prebiotic phosphorylation of nucleosides in formamide.

Authors: A M Schoffstall
Journal: Orig Life Date: 1976-12

NUCLEOTIDE SYNTHESIS UNDER POSSIBLE PRIMITIVE EARTH CONDITIONS.

1. Adsorption of 5'-AMP and catalytic synthesis of 5'-ADP onto phosphate surfaces: correlation to solid matrix structures.

2. Thermal synthesis of nucleoside H-phosphonates under mild conditions.

3. Models of prebiological phosphorylation.

Review 4. Chemical evolution. Recent syntheses of bioorganic molecules.

5. Further studies of urea-catalyzed phosphorylation reactions.

6. Phosphorylation of uridine with inorganic phosphates.

7. The fundamental nature of the genetic code: prebiotic interactions between polynucleotides and polyamino acids or their derivatives.

8. Prebiotic formation of ADP and ATP from AMP, calcium phosphates and cyanate in aqueous solution.

9. Modulation of adenosine 5'-monophosphate adsorption onto aqueous resident pyrite: potential mechanisms for prebiotic reactions.

10. Prebiotic phosphorylation of nucleosides in formamide.