| Literature DB >> 14279119 |
Abstract
Zajac, Ihor (Hahnemann Medical College, Philadelphia, Pa.), and Richard L. Crowell. Location and regeneration of enterovirus receptors of HeLa cells. J. Bacteriol. 89:1097-1100. 1965.-Treatment of live HeLa cells with chymotrypsin or trypsin completely inactivated the viral receptors for coxsackievirus B3 and poliovirus T1, respectively. Enzyme-treated cells regained their enterovirus receptor activity after incubation in culture medium. The existence of intracellular receptors for virus could not be demonstrated when live HeLa cells were treated with enzyme prior to disruption and fractionation. These results suggested that receptors for enteroviruses are limited to the cell surface.Entities:
Keywords: CHYMOTRYPSIN; COXSACKIE VIRUSES; CYTOPATHOGENIC EFFECT, VIRAL; EXPERIMENTAL LAB STUDY; HELA CELLS; POLIOVIRUS; TISSUE CULTURE; TRYPSIN
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Year: 1965 PMID: 14279119 PMCID: PMC277602 DOI: 10.1128/jb.89.4.1097-1100.1965
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490