Literature DB >> 1427864

The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species.

K Kaupmann1, J Becker-Follmann, G Scherer, H Jockusch, A Starzinski-Powitz.   

Abstract

A mouse myotube-derived cDNA encoding the Ca(2+)-dependent cell adhesion molecule M-cadherin was used to study the segregation of the corresponding gene Cdh3 in a mouse interspecific backcross. Cdh3 was found to be unlinked to the N-cadherin gene but linked to the E-cadherin (uvomorulin) locus on chromosome 8 in a region of conserved synteny with human chromosome 16q. The gene order cen-Junb-Um-Tat-(Cdh3/Aprt) was determined. The human homologue CDH3 was mapped to chromosome 16q24.1-qter by analyzing human/mouse somatic cell hybrids.

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Year:  1992        PMID： 1427864     DOI： 10.1016/s0888-7543(05)80247-2

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  10 in total

1.  High-resolution mapping of a linkage group on mouse chromosome 8 conserved on human chromosome 16Q.

Authors:  J Becker-Follmann; A Gaa; E Baùsch; E Natt; G Scherer; O von Deimling
Journal:  Mamm Genome       Date:  1997-03       Impact factor: 2.957

2.  Suppression of GSK-3β activation by M-cadherin protects myoblasts against mitochondria-associated apoptosis during myogenic differentiation.

Authors:  Yan Wang; Yanlei Hao; Stephen E Alway
Journal:  J Cell Sci       Date:  2011-11-23       Impact factor: 5.285

3.  Chromosomal localization of the murine cadherin-11.

Authors:  I Hoffman; R Balling
Journal:  Mamm Genome       Date:  1995-04       Impact factor: 2.957

4.  Allelic imbalance on 16q in small, unifocal hepatocellular carcinoma: correlation with HBV and HCV infections and cellular proliferation rate.

Authors:  L Gramantieri; D Trerè; A Pession; F Piscaglia; L Masi; S Gaiani; A Mazziotti; L Bolondi
Journal:  Dig Dis Sci       Date:  2000-02       Impact factor: 3.199

5.  Expressed cadherin pseudogenes are localized to the critical region of the spinal muscular atrophy gene.

Authors:  S Selig; S Bruno; J M Scharf; C H Wang; E Vitale; T C Gilliam; L M Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1995-04-25       Impact factor: 11.205

Review 6.  Epithelial mesenchymal transition from a natural gestational orchestration to a bizarre cancer disturbance.

Authors:  Reza Shirkoohi
Journal:  Cancer Sci       Date:  2012-12-31       Impact factor: 6.716

7.  Three independently deleted regions at chromosome arm 16q in human prostate cancer: allelic loss at 16q24.1-q24.2 is associated with aggressive behaviour of the disease, recurrent growth, poor differentiation of the tumour and poor prognosis for the patient.

Authors:  J P Elo; P Härkönen; A P Kyllönen; O Lukkarinen; P Vihko
Journal:  Br J Cancer       Date:  1999-01       Impact factor: 7.640

8.  P-Cadherin (CDH3) is overexpressed in colorectal tumors and has potential as a serum marker for colorectal cancer monitoring.

Authors:  H M C Shantha Kumara; Geoffrey A Bellini; Otavia L Caballero; Sonali A C Herath; Tao Su; Aqeel Ahmed; Linda Njoh; Vesna Cekic; Richard L Whelan
Journal:  Oncoscience       Date:  2017-10-21

9.  Allelic loss of chromosome 16q in endometrial cancer: correlation with poor prognosis of patients and less differentiated histology.

Authors:  T Kihana; N Yano; S Murao; H Iketani; K Hamada; J Yano; S Murao; H Iketani; K Hamada; J Yano; S Matsuura
Journal:  Jpn J Cancer Res       Date:  1996-11

10.  Tumor suppressor gene E-cadherin and its role in normal and malignant cells.

Authors:  Nives Pećina-Slaus
Journal:  Cancer Cell Int       Date:  2003-10-14       Impact factor: 5.722
  10 in total

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