| Literature DB >> 1427646 |
M O Savage1, C P Smith, D B Dunger, E A Gale, J M Holly, M A Preece.
Abstract
Insulin and IGF-1 production were measured throughout childhood and puberty and into adult life. Basal insulin and IGF-1 secretion increased during puberty, falling back to prepubertal levels in adulthood. However, fasting glucose levels remained constant, implying an increase in tissue resistance to insulin coinciding with puberty.Entities:
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Year: 1992 PMID： 1427646 DOI： 10.1159/000182405
Source DB: PubMed Journal: Horm Res ISSN： 0301-0163