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Literature DB >> 14276157

BIOCHEMICAL STUDIES ON HEPATIC INVOLVEMENT IN INFECTIOUS MONONUCLEOSIS.

Abstract

Eighty cases of infectious mononucleosis have been investigated by serum enzyme studies and other liver function tests. Maximum abnormalities occurred between the second and fourth weeks of illness and all tests were usually normal by the sixth week. Serum isocitric dehydrogenase activity was increased in 93% of cases and serum glutamic-oxaloacetic transaminase in 74%. Conventional liver function tests were less sensitive. Serum bilirubin was above normal in 40% of cases; in 17% of cases the increase was sufficient to show as clinical jaundice. No patient has developed chronic hepatitis.

Entities: Chemical Disease Species

Keywords: ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BLOOD ALKALINE PHOSPHATASE; BLOOD CHEMICAL ANALYSIS; ENZYME TESTS; INFECTIOUS MONONUCLEOSIS; ISOCITRATE DEHYDROGENASE; LIVER FUNCTION TESTS; SERUM ALBUMIN; SERUM GLOBULINS

Mesh：

Substances：

Year: 1965 PMID： 14276157 PMCID： PMC472868 DOI： 10.1136/jcp.18.2.209

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

13 in total

1. Serum enzymes in disease. IX. Analysis of factors responsible for elevated values in infectious mononucleosis.

Authors: D GELB; M WEST; H J ZIMMERMAN
Journal: Am J Med Date: 1962-08 Impact factor: 4.965

2. Infectious mononucleosis; an analysis of 100 cases with particular attention to diagnosis, liver function tests and treatment of selected cases with prednisone.

Authors: W R MASON; E K ADAMS
Journal: Am J Med Sci Date: 1958-10 Impact factor: 2.378

3. Transaminase and liver-function studies in infectious mononucleosis.

Authors: S B ROSALKI; T G JONES; A F VERNEY
Journal: Br Med J Date: 1960-03-26

4. [On the involvement of the liver in infectious mononucleosis. Enzyme-activity determinations in the human liver. VIII].

Authors: H KALK; E SCHMIDT; F W SCHMIDT; E WILDHIRT
Journal: Klin Wochenschr Date: 1960-05-01

BIOCHEMICAL STUDIES ON HEPATIC INVOLVEMENT IN INFECTIOUS MONONUCLEOSIS.

1. Serum enzymes in disease. IX. Analysis of factors responsible for elevated values in infectious mononucleosis.

2. Infectious mononucleosis; an analysis of 100 cases with particular attention to diagnosis, liver function tests and treatment of selected cases with prednisone.

3. Transaminase and liver-function studies in infectious mononucleosis.

4. [On the involvement of the liver in infectious mononucleosis. Enzyme-activity determinations in the human liver. VIII].

5. The liver in infectious mononucleosis.

6. Infectious mononucleosis hepatitis; a clinicopathologic study.

7. Biopsy of the liver in infectious mononucleosis.

8. Infectious mononucleosis with hepatitis.

9. A CONVENIENT METHOD FOR DETERMINING SERUM AND BILE PHOSPHATASE ACTIVITY.

10. Cirrhosis of the liver following infectious mononucleosis.

1. Infectious mononucleosis and hepatic function.