Literature DB >> 14272500

THE EFFECT OF SULFINPYRAZONE (ANTURAN) ON PLATELET ECONOMY AND BLOOD COAGULATION IN MAN.

H A SMYTHE, M A OGRYZLO, E A MURPHY, J F MUSTARD.   

Abstract

Sulfinpyrazone (Anturan) administered in therapeutic doses over a period of several weeks produced prolongation of platelet survival and reduced turnover but with little change in blood coagulation. The changes in platelet survival and turnover were associated with reduced platelet adhesiveness. It is therefore possible to affect platelet economy in man significantly, without producing corresponding effects on blood coagulation.

Entities:  

Keywords:  ARTHRITIS, RHEUMATOID; BLOOD COAGULATION TESTS; BLOOD PLATELETS; DRUG THERAPY; GERIATRICS; GOUT; MYELOFIBROSIS; MYOCARDIAL INFARCT; PHLEBITIS; PROTHROMBIN TIME; SULFINPYRAZONE

Mesh：

Substances：

Year:  1965        PMID： 14272500      PMCID： PMC1927980     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN： 0008-4409            Impact factor:   8.262


  9 in total

1.  [New observations on the correlations between hyperuricemic diathesis and arterial pathology: the place of uric acid eliminator medications in the treatment of arteriopathies of the extremities].

Authors:  C BOURDE; P BERNARD; C HANNE; J BOURDE
Journal:  Therapie       Date:  1962 Nov-Dec       Impact factor: 2.070

2.  Blood platelet economy during moderate and intensive heparin therapy.

Authors:  J F MUSTARD; E A MURPHY
Journal:  Blood       Date:  1963-07       Impact factor: 22.113

3.  Relationship between pKa and uricosuric activity in phenylbutazone analogues.

Authors:  J J BURNS; T F YU; P DAYTON; L BERGER; A B GUTMAN; B B BRODIE
Journal:  Nature       Date:  1958-10-25       Impact factor: 49.962

4.  Dicumarol therapy. Some effects on platelets and their relationship to clotting tests.

Authors:  E A MURPHY; J F MUSTARD
Journal:  Circ Res       Date:  1960-11       Impact factor: 17.367

5.  Determination of the life span of human blood platelets using labelled diisopropylfluorophosphonate.

Authors:  J A COHEN; C H LEEKSMA
Journal:  J Clin Invest       Date:  1956-09       Impact factor: 14.808

6.  Platelet economy during moderate and intensive Dicoumarol therapy.

Authors:  E A MURPHY; J F MUSTARD
Journal:  Lancet       Date:  1961-10-28       Impact factor: 79.321

7.  Effect of different dietary fats on blood coagulation, platelet economy, and blood lipids.

Authors:  J F MUSTARD; E A MURPHY
Journal:  Br Med J       Date:  1962-06-16

8.  Thrombosis.

Authors:  J C POOLE; J E FRENCH
Journal:  J Atheroscler Res       Date:  1961 Jul-Aug

9.  BLOOD COAGULATION AND PLATELET ECONOMY IN SUBJECTS WITH PRIMARY GOUT.

Authors:  J F MUSTARD; E A MURPHY; M A OGRYZLO; H A SMYTHE
Journal:  Can Med Assoc J       Date:  1963-12-14       Impact factor: 8.262
  9 in total
  26 in total

1.  Zlinkoff honor lecture: basic research, clinical research, clinical epidemiology, and general internal medicine.

Authors:  D L Sackett
Journal:  J Gen Intern Med       Date:  1987 Jan-Feb       Impact factor: 5.128

2.  Platelets in early hyperacute allograft rejection in kidneys and their modification by sulfinpyrazone (Anturan) therapy. An experimental study.

Authors:  H M Sharma; S Moore; H W Merrick; M R Smith
Journal:  Am J Pathol       Date:  1972-03       Impact factor: 4.307

3.  Enhanced drug metabolism after sulfinpyrazone treatment in patients aged 50 to 60 years.

Authors:  E Walter; C Staiger; J de Vries; E Weber; W Bitzer; M Degott; K Jüngling
Journal:  Klin Wochenschr       Date:  1982-11-15

4.  Induction of drug metabolizing enzymes by sulfinpyrazone.

Authors:  E Walter; C Staiger; J de Vries; R Zimmermann; E Weber
Journal:  Eur J Clin Pharmacol       Date:  1981       Impact factor: 2.953

5.  [Prophylaxis and therapy of shunt thrombosis in terminal renal insufficiency (author's transl)].

Authors:  H Köhler
Journal:  Klin Wochenschr       Date:  1977-01-15

6.  Biotransformation and pharmacokinetics of sulfinpyrazone (Anturan) in man.

Authors:  W Dieterle; J W Faigle; H Mory; W J Richter; W Theobald
Journal:  Eur J Clin Pharmacol       Date:  1975-12-19       Impact factor: 2.953

Review 7.  Antithrombotic drugs: part II.

Authors:  A S Gallus; J Hirsh
Journal:  Drugs       Date:  1976       Impact factor: 9.546

8.  Inhibition of primary ADP-induced platelet aggregation in normal subjects after administration of nitrofurantoin (furadantin).

Authors:  E C Rossi; N W Levin
Journal:  J Clin Invest       Date:  1973-10       Impact factor: 14.808

9.  Effect of single and multiple doses of sulphinpyrazone on antipyrine metabolism and urinary excretion of 6-beta-hydroxycortisol.

Authors:  C Staiger; F Schlicht; E Walter; U Gundert-Remy; R Hildebrandt; J de Vries; N S Wang; J Harenberg; E Weber
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

10.  Determination of sulfinpyrazone and four metabolites in plasma and urine by high pressure liquid chromatography.

Authors:  E G Lentjes; Y Tan; C A Van Ginneken
Journal:  Pharm Weekbl Sci       Date:  1985-12-13
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