Management of aspirin-sensitive rhinosinusitis-asthma syndrome: what role for aspirin desensitization?

Although aspirin is only one of the triggers of asthma attacks in patients with aspirin-sensitive rhinosinusitis asthma, aspirin sensitivity heralds severe and protracted disease requiring comprehensive management of all components of the syndrome. A review of the literature on the management of patients with aspirin-sensitive rhinosinusitis-asthma allows for the establishment of guidelines for conducting aspirin desensitization and evaluating the clinical usefulness of this procedure.