Literature DB >> 1426983

Evidence that Borrelia burgdorferi immunodominant proteins p100, p94 and p83 are identical.

H J Ditton1, M Neuss, L Zöller.   

Abstract

Recently there have been reports on high-molecular mass components of Borrelia burgdorferi, namely the p100, p94 and p83, which claimed these proteins to be specific marker antigens for the serodiagnosis of late Lyme borreliosis. The nucleotide sequences of the p100 and p83 have been published. The alignment of the deduced N-terminal amino acid sequences with the N-terminal sequence of the p94 now provides evidence that all three proteins are identical.

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Year:  1992        PMID: 1426983     DOI: 10.1016/0378-1097(92)90633-y

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN: 0378-1097            Impact factor:   2.742


  6 in total

1.  Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen.

Authors:  W S Probert; R B LeFebvre
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

2.  Epitopes shared by unrelated antigens of Borrelia burgdorferi.

Authors:  P Anda; P B Backenson; J L Coleman; J L Benach
Journal:  Infect Immun       Date:  1994-03       Impact factor: 3.441

3.  Use of a hybrid protein consisting of the variable region of the Borrelia burgdorferi flagellin and part of the 83-kDa protein as antigen for serodiagnosis of Lyme disease.

Authors:  C Rasiah; S Rauer; G S Gassmann; A Vogt
Journal:  J Clin Microbiol       Date:  1994-04       Impact factor: 5.948

4.  Establishment of enzyme-linked immunosorbent assay using purified recombinant 83-kilodalton antigen of Borrelia burgdorferi sensu stricto and Borrelia afzelii for serodiagnosis of Lyme disease.

Authors:  S Rauer; M Kayser; U Neubert; C Rasiah; A Vogt
Journal:  J Clin Microbiol       Date:  1995-10       Impact factor: 5.948

5.  Analysis of the intrathecal immune response in neuroborreliosis to a sonicate antigen and three recombinant antigens of Borrelia burgdorferi sensu stricto.

Authors:  R Kaiser; S Rauer
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1998-03       Impact factor: 3.267

6.  Protection of C3H/He mice from experimental Borrelia burgdorferi infection by immunization with a 110-kilodalton fusion protein.

Authors:  R F Bey; M E Larson; D E Lowery; B W Lee; K S Knutson; R R Simonson; V L King
Journal:  Infect Immun       Date:  1995-08       Impact factor: 3.441

  6 in total

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