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Literature DB >> 14268729

FUNCTIONAL RIBOSOMAL UNIT OF GAMMA-GLOBULIN SYNTHESIS.

Abstract

Nascent protein synthesis is associated with polyribosomes in extracts of lymph node cells removed from hyperimmunized rabbits, if the ribonuclease activity in such extracts is inhibited. Prior treatment of the cells with actinomycin D markedly decreases protein synthesis by polyribosomes.

Entities: Chemical Species

Keywords: ACTINOMYCIN; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; IMMUNIZATION; LYMPH NODES; PHARMACOLOGY; PROTEIN METABOLISM; RABBITS; RIBONUCLEASE; RIBOSOMES

Mesh：

Substances：

Year: 1965 PMID： 14268729 DOI： 10.1126/science.148.3670.646

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

13 in total

1. Influence of growth rate on protein synthesis and distribution of ribosomes in HeLa cells.

Authors: I Daskal; R Sinclair
Journal: In Vitro Date: 1975 Nov-Dec

2. The inhibition of splenic ribonuclease by liver cell extract.

Authors: P V Northup; W S Hammond; M F La Via
Journal: Proc Natl Acad Sci U S A Date: 1967-02 Impact factor: 11.205

3. SV40-specific RNA in the nucleus and polyribosomes of transformed cells.

Authors: U Lindberg; J E Darnell
Journal: Proc Natl Acad Sci U S A Date: 1970-04 Impact factor: 11.205

4. Synthesis of gamma G antibody and immunoglobulin on polyribosomes in a cell-free system.

Authors: J P Gusdon; A B Stavitsky; S A Armentrout
Journal: Proc Natl Acad Sci U S A Date: 1967-09 Impact factor: 11.205

5. Polyribosomal synthesis and assembly of the H and L chains of gamma globulin.

Authors: A L Shapiro; M D Scharff; J V Maizel; J W Uhr
Journal: Proc Natl Acad Sci U S A Date: 1966-07 Impact factor: 11.205

6. The in vitro activity of the microsomal fraction isolated from the spleen and the lymph nodes after immunization of the donor.

Authors: M Hrubesová
Journal: Folia Microbiol (Praha) Date: 1966 Impact factor: 2.099

FUNCTIONAL RIBOSOMAL UNIT OF GAMMA-GLOBULIN SYNTHESIS.

1. Influence of growth rate on protein synthesis and distribution of ribosomes in HeLa cells.

2. The inhibition of splenic ribonuclease by liver cell extract.

3. SV40-specific RNA in the nucleus and polyribosomes of transformed cells.

4. Synthesis of gamma G antibody and immunoglobulin on polyribosomes in a cell-free system.

5. Polyribosomal synthesis and assembly of the H and L chains of gamma globulin.

6. The in vitro activity of the microsomal fraction isolated from the spleen and the lymph nodes after immunization of the donor.

7. [The in vitro synthesis of gamma globulin by lymphocytes after stimulation with phytohemagglutinin].

8. Immunoglobulin assembly in a mouse myeloma.

9. Identical allotypic markers of heavy polypeptide chains present in different immunoglobulin classes.

10. Biosynthetic and structural studies of a heavy chain disease protein.